VAD方案治疗多发性骨髓瘤的疗效观察论文.pdf

⑧浙江大学医学院专业学位硕士论文 The observationofVAD inthetreatment efficacy regimen of multiplemyeloma Abstract evaluatetheclinical ofVAD in Purpose：To efficacy regimen thetreatment with ofmultiplemyeloma(MM)．Methods：22patients were treatedwithVAD solution multiplemyeloma regimen．VAD consisted The ofVADwereevaluatedaftersixcontinuous efficacy regimen treatmentcourses．Evaluationindexsincluderesultsofserum myeloma marrow protein(M--protein)；creatine；bone myelomacell；peripheral blood countsetal．Thesidereactionswererecorded．The therapeutic effectivenesswasclassifiedinto and partialremisson，improvement uneffect．Result：11casesachievedremisson．9cases partial casesuneffect．Thetotal ratewas90．9％． improvement，2 response Conclusion：VADintreatment are re百mell ofmultiplemyeloma and sideeffects．Itis for significant clinical rapidresponse，less worthy widespreadgeneralization． Words Key Multiple myeloma；VADregimen 2 ⑧浙江大学医学院专业学位硕士论文 多发性骨髓瘤是一种浆细胞恶性增生性疾病，发病率占造血系统 得很好疗效，国内亦有相继报道。本文对初发删患者应用VAD方案， 疗效显著，现报道如下。 1对象和方法 初发患者共22例。临床诊断标准依据张之南主编的血液病诊断中蹦 ⅡI期，分无肾功能损害为A组、有肾功能损害为B组。根据上述标准临 床定为I 型9例，轻链型5例．男性11例，女性11例，年龄38—7