第十一章 枕骨大孔-第二颈段血管周细胞瘤1例报道并文献复习.PDF

临床与病理杂志 2015, 35(3) 500 J Clin Path ol R e s doi: 10.3978/j.issn.2095-6959.2015.03.032 ·临床病例讨论· View this article at: /10.3978/j.issn.2095-6959.2015.03.032 枕骨大孔-第二颈段血管周细胞瘤1例报道并文献复习 刘翠，许春伟，张博，邵云，姜春婷，王怀涛，王海艳，吴永芳，李晓兵，张彤 (军事医学科学院附属医院理科，北京 100071) [摘　要] 目的：探讨血管周细胞瘤的临床病理学特点及诊断要点。 方法：对 1例血管周细胞瘤进行临床资 料、病理形态学及免疫组化观察，并结合文献对其诊断及鉴别诊断进行探讨。 结果：本例镜下观 肿瘤细胞为梭形，血管丰富，形成弥漫的网状结构，鹿角状的血管将肿瘤细胞分割小叶状，瘤细 胞体积较大，胞浆丰富，边界不清，核呈圆形、卵圆形，病理性核分裂相多。免疫组化染色结果 显示肿瘤细胞Vimentin(+) 、CD34(+) 、FVIII(+) 、S-100( − ) 、CEA(− ) 和GFAP(− ) 。结论：血管周 细胞瘤，非常少见，因此缺乏对其认识，从而易与其他肿瘤混淆导致误诊。提高对血管周细胞瘤 的认识，对避免误诊是至关重要的。 [关键词] 血管周细胞瘤；病理学；临床；免疫组化 A case report and literature review on foramen magnum- the second cervical segment hemangiopericytoma LIU Cui, XU Chunwei, ZHANG Bo, SHAO Yun, JIANG Chunting, WANG Huaitao, WANG Haiyan, WU Yongfang, LI Xiaobing, ZHANG Tong (Department of Pathology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, China) Abstract Objective: To explore the characteristics of clinicopathology and diagnostic criteria about hemangiopericytoma. Methods: The clinical data, histopathologic observation and immunohistochemical staining were studied in one case of foramen magnum- the second cervical segment hemangiopericytoma, in order to explore its diagnosis and differential diagnosis combined with literatures. Results: Microscopic examination of this case showed that the tumor cells were fusiform with rich blood vessels and they formed a