功能性神经元诱导方法.pdfVIP

Neurochemistry International 55 (2009) 323–332 Contents lists available at ScienceDirect Neurochemistry International jour nal homepage: www.els evier .c om /loc ate/n eu int Simultaneous PKC and cAMP activation induces differentiation of human dental pulp stem cells into functionally active neurons ´ a ´ a ´ b ´ ´ ´ a ´ c ´ ´ a,e Marianna Kiraly , Balazs Porcsalmy , Agnes Pataki , Kristof Kadar , Marta Jelitai , Balint Molnar , ´ d ´ e f g ´ b ´ a,* Peter Hermann , Istvan Gera , Wolf-Dieter Grimm , Bernhard Ganss , Akos Zsembery , Gabor Varga a Department of Oral Biology, Semmelweis University, Budapest, Hungary b Institute of Human Physiology and Experimental Research, Semmelweis University, Budapest, Hungary c Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary d Department of Prosthodontics, Semmelweis University, Budapest, Hungary e Department of Periodontology, Semmelweis University, Budapest, Hungary f Department of Periodontology, University of Witten-Herdecke, Germany g CHIR Group in Matrix Dynamics, University of Toronto, Canada A R T I C L E I N F O A B S T R A C T Article history: The plasticity of dental pulp stem cells (DPSCs) has been demonstrated by several studi