缺血性脑血管病的抗医栓治疗.pptVIP

缺血性脑血管病的抗栓治疗 ;内容;亚太地区脑卒中发生率;;;Zhu Chen, The Third National Survey on the cause of death. Ministry of Health, People‘s Republic of China. Peking Union Medical University Press 2008;ODonnell MJ,et al. Lancet. 2010;376(9735):112-23.;;;;TIA 或小卒中后卒中的复发危险 BMJ 2004; 328: 326-328;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;临床试验研究证明;内容; 抗栓治疗; 第一代溶栓药 链激酶（streptokinase, SK） 尿激酶（urokinase, UK） 第二代溶栓药 r-tPA 单链尿激酶型纤维蛋白溶酶原激活 剂（single chain urokinasetype plasmogen activator, scuPA） ;2013年AHA/ASA急性脑卒中早期治疗指南-溶栓;;抗凝治疗;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;AF者的危险分级;2013年AHA/ASA急性脑卒中早期治疗指南-抗凝治疗建议;心源性栓塞的抗栓治疗——;内容; 抗血小板治疗 ;;;脑梗死 复发率;;缺血性卒中急性期早期应用阿司匹林 ;2013年AHA/ASA急性脑卒中早期治疗指南;TIA 和小卒中患者早期卒中复发危险;ATC2009荟萃分析——阿司匹林明显降低缺血性脑卒中发生率;;1. CAPRIE Steering Committee. Lancet 1996; 348: 1329–1339. 2. Antiplatelet Trialists Collaboration. BMJ 2002; 324: 71–86.; 研究卒中亚组分析氯吡格雷疗效并不优于阿司匹林;CAPRIE亚组研究;ESRS：0-3分低危，4-6分中危，7-9分极高危;阿司匹林与氯吡格雷出血风险无差异;;;Inclusion Criteria Ischemic stroke/TIA in prior 3 months ≥1 risk factors in past 3 years: Ischemic stroke MI Angina pectoris Diabetes mellitus Symptomatic PAD Exclusion Criteria Age 40 years Severe comorbid conditions Increased risk of bleeding Scheduled for major s