戈舍瑞林联合曼月乐治疗子宫腺肌病效果评价.docVIP

戈舍瑞林联合曼月乐治疗子宫腺肌病效果评价 　　[摘要]目的 探?戈舍瑞林联合曼月乐治疗子宫腺肌病的效果。方法 将2014年2月～2015年2月在我院妇科治疗的70例子宫腺肌病患者随机分为观察组和对照组，每组各37例。对照组单用戈舍瑞林治疗，观察组采用戈舍瑞林联合曼月乐治疗。比较两组患者的治疗效果、子宫各项指标、痛经及月经改善情况；观察两组的不良反应。结果 观察组治疗有效率为94.29%，显著高于对照组的85.71%，差异有统计学意义（P0.05）。结论 戈舍瑞林联合曼月乐治疗子宫腺肌病的效果显著，能够直接作用于子宫病灶，抑制子宫内膜的异常生长，减轻病灶活性，改善临床症状，有效避免了手术治疗，具有积极的临床意义 [关键词]子宫腺肌病；戈舍瑞林；曼月乐；疗效评价 [中图分类号] R711.74 [文献标识码] A [文章编号] 1674-4721（2016）12（a）-0095-03 Effectiveness evaluation of Goserelin combined with Mirena in the treatment of adenomyosis WU Yi-xue ZHONG Jian-ye YANG Xiu-yun Department of Gynaecology，Maternal and Child Care Service Centre of Huidong County，Guangdong Province，Huidong 516300，China [Abstract]Objective To study the efficacy of goserelin combined with Mirena in the treatment of adenomyosis.Methods Seventy patients with adenomyosis treated in the gynaecology department of our hospital from February 2014 to February 2015 were randomly divided into control group and observation group，with 37 cases in each group.The control group was treated with Goserelin，observation group was treated with Goserelin combined with Mirena.The treatment effect，indicators of uterine，dysmenorrhea and situation of menstruation of patients were compared between the two groups；the adverse reactions of two groups were observed.Results The effective rate of the observation group was 94.29%，significantly higher than that of the control group （85.71%），the difference was statistically significant （P0.05）.Conclusion Goserelin combined with Mirena has significant effect in the treatment of adenomyosis，can directly effect on uterine lesions，inhibit abnormal growth of endometrial，reduce disease activity，improve clinical symptoms，avoid the surgery effectively，has positive clinical significance. 　　[Key words]Adenomyosis；Goserelin；Mirena；Therapeutic evaluation 子宫腺肌病为临床育龄期妇女常见疾病，是指在多种因素的刺激下，子宫内膜腺体和间质侵入子宫肌层，造成弥漫性病变。本病呈进行性加重，临床表现为痛经、月经过多、贫血、性交痛等，B超检查可见子宫增大，严重者甚至发生不孕，影响正常生活和心理健康[1]。本病的治疗手段较多，其治疗主要取决于病情的轻重、合并症情况、有无生育要求等[2]。对于要求保留生育功能