老年患者静吸复合麻醉深度术后认知功能观察.docVIP

老年患者静吸复合麻醉深度术后认知功能观察 　　摘要：目的 探讨静吸复合麻醉深度与老年患者术后认知功能的相关性。方法 选择进行择期手术需行静吸复合麻醉的65岁以上老年150例，将患者分为A组、B组和C组。比较三组在术前1 d，术后1 d、2 d的认知功能评分。结果 术前1 d，三组MMSE评分和TMT评分差异无统计学意义，术后1 d、2 d三组MMSE评分、数字广度测验和TMT评分在时间、组间、交互上比较差异有统计学意义，B组术后1 d、2 d MMSE评分均高于A组和C组，TMT评分均低于A组和C组。结论 静吸复合麻醉深度与老年患者认知功能存在相关性，当测定BIS值在40～50范围内，对机体认知功能的影响较小，可用于指导临床治疗 关键词：认知功能障碍；静吸复合麻醉；深度 Observation of Postoperative Cognitive Function in Elderly Patients with Deep Anesthesia Combined with Anesthesia YOU Chun-zhi （Department of Anesthesiology，Jiujiang First People’s Hospital，Jiujiang 332000，Jiangxi，China） Abstract：Objective To investigate the correlation between the depth of anesthesia and postoperative cognitive function in elderly patients.Methods Elective surgery for anesthesia of 65 years of age or older in 150 cases，the patients were divided into A group，B group and C group.The three groups were compared before operation，1 d，1 d after operation.2 d cognitive function score.Results Before operation，1 d，three groups had no statistically significant differences in MMSE score and TMT score， postoperative 1 d，2 d，three groups of MMSE score，TMT score and digit span test in time between groups，the difference was statistically significant interaction on the B group，1 d after operation.2 d MMSE were higher than that of A group and C group，TMT scores were lower than A group and C group.Conclusion Intravenous Inhalation Anesthesia in elderly patients with cognitive depth correlation function，the determination of BIS value in the range of 40～50，the smaller effect on the cognitive function，which can be used to guide the clinical treatment. Key words：Cognitive dysfunction；Intravenous Inhalation Anesthesia；Depth ?g后认知功能障碍（Postoperative Cognitive Dysfunction，POCD）是老年患者术中麻醉后常出现的一种并发症，严重影响患者术后效果及出院后的生活质量。据统计，POCD患者发展为痴呆的风险较高，是认知功能正常老年人10倍以上[1]，与老年患者术中麻醉情况紧密相关。为探讨静吸复合麻醉深度与老年患者术后认知功能的相关性，本研究选取我院收治的150例老年患者进行研究，现报道如下 1 资料与方法 1.1一般资料 本研究入选150例患者，均为2015年7月～2016年6月在我院行择期需行静吸复合麻醉老年患者。其中男70例，女80例，年龄65岁以上，ASA分级在Ⅰ～