记忆性T细胞与HIV疫苗.pdf

2007 5 May, 2007 17 5 CHINESE JOURNAL OF COMPARATIVE MEDICINE Vol.17 No. 5 T HIV 王 卫, 魏 强 ( , 100021) = HIV HIV , , HIV T HIV T HIV = T ; T ; T ; HIV = R392 = A = 1671-7856(2007)05-0292-05 Memory T Cell and HIV Vaccine WANG Wei, WEI Qiang (Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Peking Union Medical College, eijing 100021, China) = Abstract The vaccines are consideredas an useful approach for preventing theAIDS. Most of the past HIV vaccines only induced the body to product the memory cell and antibody, but don. t to prevent HIV from infecting the body. The strategy on development of vaccines against HIV basing on memory T cells could bring new hope to human vaccination. In this review, the classification, differentiation, formation and duration of memory cells, and also the possible target role for development vaccines will be presented. = Key words Memory T cell; Effector memory T cell; Central memory T cell; HIV vaccine 2005 , , 4030 , 2005 490 2005 , [ 1] 310 1985 HIV , 2005 , HIV 65 , AIDS 715 2005 , 1 HIV [ 2] 1986 HIV , HIV , , HIV , , : HIV , , ( inactivated viruses) (attenuated vaccines) ( live , vectorbased vaccines) , HIV