覆盘子酮技术参数及合成方法.doc

覆盘子酮 Registry Number: 104-20-1 Formula: C11 H14 O2 CA Index Name: 2-Butanone, 4-(4-methoxyphenyl)- Other Names: 2-Butanone, 4-(p-methoxyphenyl)- (6CI,7CI,8CI); 1-(4-Methoxyphenyl)-3-butanone; 1-(p-Methoxyphenyl)-3-butanone; 4-(4-Methoxyphenyl)-2-butanone; 4-(p-Methoxyphenyl)-2-butanone; 4-Methoxybenzylacetone; Anisylacetone; ENT 20279; NSC 405366; Raspberry ketone methyl ether; p-Anisylacetone Boiling Point 285 ℃ (1) CAS Boiling Point 277 ℃ (2) CAS Boiling Point 177 ℃ Press: 25 Torr (3) CAS Boiling Point 166-167 ℃ Press: 17 Torr (4) CAS Boiling Point 154 ℃ (1) CAS Boiling Point 138 ℃ Press: 0.200 (5) CAS Torr Boiling Point 120-122 ℃ Press: 3 Torr (6) IC Boiling Point 110 ℃ Press: 1 Torr (7) CAS Boiling Point 105 ℃ Press: 0.5 Torr (7) CAS Boiling Point 100-103 ℃ Press: 0.23 Torr (8) IC Boiling Point 95 ℃ Press: 0.5 Torr (9) IC Boiling Point 72 ℃ Press: 0.075 Torr (10) IC Registry Number: 250039-10-2 Component Registry Number: 123-11-5 Formula: C8 H8 O2 Formula: (C8 H8 O2)2 CA Index Name: Benzaldehyde, 4-methoxy-, dimer (9CI) Preparation of aromatic carbinols from aldehydes. Kido, Yoichi; Hamazaki, Takashi; Yoneda, Koichi; Ohnishi, Takashi. (Kuraray Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho (2000), 7 pp. CODEN: JKXXAF JP 2000103754 A Patent written in Japanese. Application: JP 98-291502 Priority: . CAN 132:264958 AN 2000:232587 CAPLUS Abstract ArCH2CH2CRMeOH [I; Ar = [(fluoro)alkyl-, alkoxy-, OWO-substituted] Ph, naphthyl, furyl; W = alkylene; R = hydrocarbyl], useful as fragrances (no data), are prepd. by reaction of ArCHO (Ar = same as I) with H and Me2CO in the presence of bases and hydrogenation catalysts and reaction of ArCH2CH2COMe (Ar = same as I) with RMgX (R = same as I; X = halo). Reaction of PhCHO with Me2CO under H in the presence of Pd/C and NaOH at 80? under 7.0 kg/cm2 gave 81.4% PhCH2CH2COMe, which was treated with MeMgCl in THF at 5? to room temp. to give 76.