凝血3项生物参考区间验证的实验探讨.pdfVIP

2426 重庆阪学 2009 年 10 月第 38 卷第 19 期 • I临床研究· 凝血 3 项生物参考区间验证的实验探讨 白 泉，徐华建，李胜友，张莉萍A (重庆医科大学附属第一医院检验科 400016) 摘 要:目的 对实脸盆凝血检测项阁血浆凝血画鲁派时间(PT、活化部分凝血活酶时间 (APTT) 、纤维蛋白$. (FBG) 现用的 生物参考民间进行验证，确保其适用于临床。方法 根据纳入标准选择使成参考个体 20 名，采集符合要求对象栋本，按实验室标 准操作手册(SOP)要求进行规范检测，采用性能评价符合要求的 Sysmex CA7000 血凝仪枪测标本。街果 参与验证的 3 个项目 中 .20 名健康参考个体 100%结采落在现用参考鼠间内。结论 本次验证项目现用的生物参考区间适用于本实验室，可以继续使 用。实跄室应建立完善、规范的验证制度、程序，保证生物参考区间的适用蚀。 关键词:生物参考陈闷 p 健康参考个体4 验证 Jt j就编号 :1671喃8348(2009)19-2426-02 中阁分提号:R446.112 文献标识码:A Study 00 the validation for biology reference intervaJ of PT APγr.and FBG BAI Yao .XU Hua-jían. Lí Sheng-fa ,et al. (Ðeþartment of Cliníc Laboratory ,the Fírst Affiliated Hosρital of Chongqing Medical University ,Chongqing 400016 ,China) Abstract:Objective To validate the biology reference interval of prothrombin time{PT) ,activated partial thromboplastin time (AP丁丁) ,fibrinogen(FBG) .and ensure their c1 inical applìcation. Meth叫s According to selective standard. 20 health reference indi翩 viduals were chosen. The blood samples were detected by the automatic blood coagulatíon analyzer Sysmex CA7000 according to the laboratory SOP operation document requíring. Results In 3 verified project绢. all results of 20 reference índividuals samples were withín the biology reference ínterval being used. Cooclusion 丁he biology reference interval being used is suitable for our laboratory and can contínue to be used. To maíntain c1inícal app [ication.a standard and consummate verification system and program should be estab !ished ín laboratory. Key words: biology reference interval; reference individual; validation 生物参考阪问是解释检验捕果是沓正常的依据，按照国际