RNA 干涉在提高植物营养价值上的应用 - 植物研究.PDF

生物技术通报 BI OTECHN OLOG Y B ULLETI N 2005 3 RNA 刘宾 蒋继志 廖祥如 韩国辉 史海水 ( , 071002) : RNA 干涉( RNAi) 是由具同源性的外源 dsRNA 引起的序列特异性转 后基因沉默现象, 广泛存在 于各种动植物中人类大多数疾病, 像心脏病和癌症, 都能够通过食用添加具有特殊营养成分养的饮食来预防 应用RNAi技术可为人和动物提高植物的营养价值 : RNAi dsRNA siRNA RISC RdRP Dicer The Application of RNAi in Improving Plant Nutritional Value Liu Bin Jiang Jizhi Liao iangru Han Guohui Shi Haishui ( F acul ty of L if e Sc ienc e , H e bei Univ er s ity , Baodi ng 071002 ) Abstract: RNAi(RNA interference) is a phenomenon of specifical postranscriptional gene silencing mediated by induced dsRNA with homogenous sequences , which operates extensively in both plants and animals. Some major human diseases, such as heart disease and cancer, can be prevented by dietary supplements of specific nutrients. It can improve the nutriti onal value of plants for human and animal nutrition through RNAi. Key w ords: RNAi dsRNA siRNA RISC RdRP Dicer , , RNAi , RNAi, dsRNA , mRNA dsRNA , [3] RNAi , , [ 1] 1 RNAi , 1. 1 RNAi 的机制 20 90 , Arizona Jorgensen , , , [2] , , , 8 , Graig Mell An 1998 ,dsRNA ( RNAi) mR drew Fire NA , dsRNA dsRNA [4] , RNAi RNA , RNAi, : : , , : : ( 1977) , , , : 32 生物技术通报B