我院抗高血压药使用情况调查探究.docVIP

我院抗高血压药使用情况调查探究[摘要] 目的：评价我院抗高血压药物的使用情况，为临床合理用药提供依据。方法：收集2009~2010年我院抗高血压药物资料并对数据进行统计、分析。结果：我院最常用的抗高血压药物为钙离子通道阻滞剂，而血管紧张素转换酶抑制剂、血管紧张素Ⅱ受体拮抗剂、β受体阻滞剂的使用频率相当；2009~2010年我院抗高血压药的销售金额呈上升趋势；2009、2010年销售金额最多的抗高血压药物分别为氨氯地平片和左旋氨氯地平片，药物利用指数分别为0.50、0.25；2009、2010年用药频度居第1位的抗高血压药物均是硝苯地平缓释片，药物利用指数分别为8.00、10.00。结论：我院抗高血压药应用基本合理 [关键词] 抗高血压药；用药频度；药物利用指数 [中图分类号] R544.1 [文献标识码] C [文章编号] 1673-7210（2011）12（a）-151-02 Investigation of antihypertensive drugs service condition in our hospital WEN Jiufang Department of Pharmacy, the First People’s Hospital of Jingzhou City, Hubei Province 434000, China [Abstract] Objective: To evaluate the service condition of antihypertensive drugs in our hospital, in order to provide basis for clinical rational drug use. Methods: The data of antihypertensive drugs application in our hospital from 2009 to 2010 was collected, and statistical analysis was conducted. Results: In our hospital, the most common application of antihypertensive drug was calcium channel blockers, operating frequency of angiotensin-converting enzyme inhibitors, angiotensin Ⅱ receptor antagonist, β receptor antagonist were close. The sales amount of antihypertensive drugs increased form 2009 to 2010 in our hospital, Amlodipine pieces and Levorotatory Amlodipine pieces was occupied the most sales amount of antihypertensive drugs in 2009 and 2010 respectively, and DUI was 0.50 and 0.25 respectively. Nifedipine was occupied the first position of the DDDs among all antihypertensive drugs, DUI was 8.00 and 10.00 respectively. Conclusion: The application of antihypertensive drugs in our hospital is basic reasonable. [Key words] Antihypertensive drug; DDDs; Drug utilization index 高血压是以循环动脉压增高为主要表现的临床综合征，是常见的心血管疾病，已成为人类健康的隐形杀手。2005年中国约16%的人口患有高血压，总人数达1.8亿[1]。近年来高血压的发病率有增高趋势，60岁以上老年人高血压发病率为40%以上[2]。高血压是多种心血管疾病的重要病因和危险因素，影响重要脏器如心、肾、脑的结构与功能，最终可导致器官的功能衰竭，迄今仍是心血管疾病死亡的主要原因之一[3]。为了解高血压临床用药情况及动态变化，本文对我院2009~2010年抗高血压药的用药频度（DDDs）、药物利用指数（DUI）等相关数据进行了统计与分析，以期为临床合理、有效、安全、经济用药提供参考。现报道如下