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1559T_ch26_454-468 10/20/05 15:39 Page 454
26
Amino Acids, Peptides, Proteins, and Nucleic Acids:
Nitrogen-Containing Polymers in Nature
Here it is: the last chapter! It is, however, as much a beginning as an end. Chemistry in general, and organic
chemistry in particular, are not isolated fields. Organic chemistry is the basic stuff of biology, and this chapter
bridges the two. The basic principles that govern the behavior of organic molecules in general are shown here
to be directly applicable to molecules of greater and greater complexity. You see here some of the most fun-
damental molecules of life viewed from the organic chemist’s point of view. The next step in this direction is
biochemistry.
Outline of the Chapter
26-1 Structure and Properties of Amino Acids
Nature’s most versatile building blocks.
26-2, 26-3 Preparation of Amino Acids
Fancy footwork involving two very different functional groups.
26-4 Peptides and Proteins: Amino Acid Oligomers and Polymers
The whole is greater than the sum of its parts.
26-5 Determination of Polypeptide Primary Structure: Sequencing
Exercises in logic, plus a lot of hard work.
26-6, 26-7 Synthesis of Polypeptides: A Protecting Group Challenge
Even fancier footwork; how does Nature do it so easily??!!
26-8 Polypeptides in Nature: The Proteins Myoglobin and Hemoglobin
26-9, 26-10 Biosynthesis of Proteins: Nucleic Acids
How Nature appears to do it so easily.
26-11 DNA Sequencing and Synthesis: Gene Technology
The fut
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