双波长法测定马来酸氨氯地平的含量.pdfVIP

协1.37 NO.3 电子科技大学学报 第 37 卷第3 期 2008年5月 JOUI机器1 ofUniversity ofElectronic Science 船d Technology ofChin辑 May 2008 ·生物电子学· 双波长法测定马来酸氨氯地平的含量 友都灵，学雷芳 {电子科技大学微电子与阎体咆子学院成都 61ω54) 、 E搞萤1 为了建立…种简侠、快速、价廉的马来酸氨氯地平片的含量相测定方法，该文采用.:l示分点龙成法(42Snm和365 nm为测定双波长)测定马来酸...氯地乎片剂中马来戴在氯地乎的含量，线性区间为5.0 耐 50.0 四时，回收率为99.92%， RSD为 0.67% .该方法既能有效消除辅料混浊溶液的干扰，又简便‘快速、准确. 共键词马来酸戴氯地乎;马来酸.l.氯池子片;差示分光先J.t法;混浊溶液 中理分提号 R921 .l 文献梅i只码 A Determination ofAmlodipine Maleate in Tablet by Differential Spectrophotometry XIA Du-ling and LI Xue-fang 。你001 ofMicroele衍onics and Solid-State Elωtroni邸. Uníversity ofEI伺tronic Scienωand D时mology ofChina Chengdu 61ω54) Abstract Amlodipine maleate is a new kind ofmedicine for hypertensive disease. This article mainly studies the conditions of quantitatively measuring amlodipine maleate of tablet. The double-wave. 365 nm and 425 lllll, spec肌肉。ωme句w;出 used 岛T determining the content of the amlodipine maleate tablet to eliminate interference of excipient. The absorbance is we I1 linear with concentration between 5.0 Jlglml and 50.0μg/ml， and the linear equation of differential spectrophotome句 is tlA 嚣0.0l 149C+O.003 ( 1明0.9994)，世le coefficient of recovery is 99.92%, and RSD is 0.67%. Key words amodipine maleate; amodipine mal相te tablets; d旧社rential spectrophotome均气 n叩，heloid solution 氮氧地平片是一种新型的长效双氢地塔吉类钙离 二三分析议器厂). WS70斗黯红外快速干烧箱(成都科 子拮拉姆，对治疗高血压有长效援释作用(1 剖， 2002 学仪器厂}:试齐u 采用马来酸氯氮地平对照品 年全球销售额排间药物首位。马来酸氮氧地平白氮 (Amlodipine Maleate)的硬脂酸镜φ1agesium stearate) 氧地平和马来股成盐而