服避孕药在不孕症治疗中的应用进展（国外英文资料）.docVIP

服避孕药在不孕症治疗中的应用进展 ? expert forum The application of oral contraceptives in the treatment of infertility Tian An oral contraceptive pill based on estrogen and progesterone (oral OC (contraception), since the advent of white, has made thousands of women The woman got rid of the pain caused by the unexpected pregnancy and realized the master of the woman Dynamic contraception. In recent years, except for the contraceptive effect of OC, people Attention has also begun to be paid to the use of OC in womens non contraceptive fields This article mainly expounds the effect of 0C on ovulation induction in infertile patients Fruit. Application of OC in anovulatory patients In 1970s, people began using 0C for the pituitary gland Suppression of ovarian axis n], feedback induced spontaneous ovulation treatment Anovulatory infertility. Studies have found that in follicular dependent gonadotropin producing Long before progesterone can inhibit follicular growth and development [2]. Simultaneous pregnancy shock Biotin also inhibits the binding of FSH to granulosa cells and inhibits it Granulosa cells produce estrogen. For wHO II type anovulation patients, that is, normal FSH A patient who is anovulatory because of prolonged lack of progesterone in the body The number of small follicles in nests was basal, E. High level. OC for this part The patient provides progesterone, which helps suppress estrogen in the body Produce, especially after prolonged OC treatment, in patients with follicles Early FSH levels were shorter in patients treated with 0C or without OC Elevated levels of FSH in patients with type II anovulation, After stopping OC, the high FSH, low E: level is beneficial to induce self Ovulation. Clomiphene (clomiphene citrate, CC) for the treatment of The first-line drugs for anovulatory patients have been 60 years old, but... 20% of the patients with CC showed CC resistance, for this In some patients, gonadotropin (gonadotropin) is usually selected, (Gn) or ovarian drilling a