昌平区2006年麻疹和风疹疑似病例血清学检测结果分析.pdfVIP

中国卫生检验杂志2007年l2月第l7卷第l2期 Chinese Journal of Health Laboratory Technology，Dec 2007；Val 17 No 12 【监测报告】 昌平区2006年麻疹和风疹疑似病例血清学检测结果分析 牛桓彩，马文军 (北京市昌平区疾病预防控制中心，北京 1022oo) 【摘要] 目的：了解昌平区麻疹、风疹疑似病例的血清学实验室诊断符合率和血清流行病学特征，为进一步提高麻疹、风 疹的病例诊断提供依据。方法：应用酶联免疫吸附试验检测血清标本中麻疹或风疹IgM抗体。结果：2006年共检测麻疹 疑似病例血清175例，检出麻疹IgM抗体阳性55例，实验室诊断符合率为31．4％，在其余麻疹IgM抗体阴性的120例病 例中检出风疹IgM抗体阳性34例，检出率为28．3％。检测风疹疑似病例血清172例，检出风疹IgM抗体阳性75例，实验 室诊断符合率为43．6％，在其余风疹IsM抗体阴性的97例病例中检出麻疹IgM抗体阳性3例，检出率为3．1％。麻疹、 风疹疑似病例与实验室诊断病例的发病时间均集中在3—6月份；年龄均以20—24岁组最多；外地户籍和无疫苗接种史 或接种史不详的麻疹和风疹病例占80％以上。结论：我区麻疹疑似病例实验室诊断阳性符合率为31 4％，低于国内相关 报道I1]。风疹实验室诊断阳性符合率为43．6％，与国内相关报道相同 ]，存在误诊漏诊现象；外地户籍和无疫苗接种史 或接种史不详的麻疹和风疹病例占80％以上。 [关键词] 麻疹；风疹；血清学检测 [中图分类号] R446．11 [文献标识码] B [文章编号] 1004—8685(2007)12—2285—03 Analysis of serological testing data of measles and rubella suspected case in Changping District in 2o06 Niu Huan-cai，Ma耽 n (Changping Center for Disease Control and Prevention，Beijing 102200，China) [Abstract] Objective：To understand the accuracy of laboratory diagnosis of measles and rubella suspected case and epidemio- logical characteristics in Changping District to provide bases for case diagnosis．Methods：Detection of serum anti—treponema pal— lidum IgM antibody in patients tll measles and rubella Was performed by using ELISA．Results：The serum of 175 suspected measles cases were detected in 2006．55 had been tested IgM positive．The rate of definitive laboratory diagnosis Was 31．4％．The rest measles samples were 34 positive of IgM antibody of rubella．The detective rate is 28．3％．Among the 172 cases of suspected rubella．75 cases showed positive rubella IgM．The rate of definitive diagnosis Was 43．6％．Among the other 97 cases of the nega— tive IgM antibody of