实习课 病例对照研究111.ppt

信息偏倚 回忆偏倚 病例对照研究的主要弱点，很难完全避免 information bias Recall bias The main weakness of case control study, difficult to avoid completely * 混杂偏倚（confounding bias) 病例对照研究遇到很多混杂因素 不易识别 不易确定 控制 混杂因素作为匹配因素 分层分析 进行多因素分析 限制 Encounter a lot of confounders Difficulty to identify Difficulty to confirm Control Matching Stratified analysis Multivariate analysis Restriction * 二、对照选择中的偏倚Bias in selecting control 选择的对照缺乏代表性 与所研究的可疑病因有关的其它疾病病人作为对照 有意不暴露于可疑病因的疾病病人作为对照 Lack of representatives of control Controls are patients with disease which related suspected factors Patient may consciously not expos