无模板法制备三维互联大孔羟基磷灰石 - journal of northeastern .pdf

第32 卷第11期 东 北 大 学 学 报 ( 自 然 科 学 版 ) Vol. 32, No. 11 2 0 1 1 年 11 月 Journal of North ast rn U niv rsity( Natural Sci nc ) N ov. 2 0 1 1 茹红强, 楚宝帅, 林春青, 陈 思 ( , 110819) : ( PA F) ( HA) , PAF . X : HA , HA . ( SEM) : HA HA PVA ; PVA HA 4. 4 49 HA , HA , 90~ 200 m, , . : ; ; ; : T B 335 : A : 1005-3026( 2011) 11- 1587-04 Non- templated Preparation of 3D- interconnected Macroporous Hydroxyapatite R UH ong-qiang, CH U Bao-shuai, LIN Chun-qing, CHEN Si ( School of Mat rials M tallurgy, North ast rn Univ rsity, Sh nyang 110819, China. Corr sponding author: RU Hong-qiang, E-mail: ruhq @ smm. n u. du. cn) Abstract: A nov l synth sis m thod, call d poly ( vinyl alcohol) assist d foaming m thod ( PAF m thod) for th pr paration of porous hydroxyapatit ( HA) scaffolds with 3D-int rconn ct d macropor s w ithout using any t mplat s or porog ns or complicat d ch mical proc ss was r port d. XRD analys s r v al d that th sint r d macroporous HA is pur in compositions. SEM and CLSM r sults show d that th macroporous structur s and por siz s can b facil ly tun d by adjusting th mass ratios of PVA to HA. T h mass ratios PVA to HA of 4. 4 and 4. 9 produc macroporous HAs w ith uniformly distribut d macropor s w ith siz s ranging from 90 to 200 m in siz s, w hich ar similar to thos of human bon in t rms of macropor siz and int rconn ctivity . It is th r for b li v d that such kind of 3D int rconn ct d macroporous HA scaffolds hav gr at pot ntial for application in th ar a of bon tissu ngin ring. Key words: non-t mplat d; macroporous; hydroxyapatit ; 3D- int rconn ct d ( hydroxyapatit , HA) , HA Ca ( PO ) ( OH) , . , 10 4 6 2 . 5