支撑喉镜下CO2激光微创手术治疗早期喉癌的疗效分析 - tumor - 肿瘤.PDF

肿瘤2013 年10 月第33 卷第10 期　TUM OR Vol. 33, October 2013　　 909 DOI: 10.3781/j .issn.1000-7431.2013.10.011 Copyright© 2013 by TUM OR Clinical Research 临床研究· 支撑喉镜下CO 激光微创手术治疗早期喉癌的疗效分析 2 高树峰，张少容，刘月辉，杨春平，罗　英 南昌大学第二附属医院耳鼻咽喉头颈外科，江西南昌　330006 [摘要]　目的：探讨CO2 激光微创手术治疗早期喉癌的疗效。方法：回顾性分析2003 年4 月—2008 年4 月 接受CO2 激光微创手术治疗的186 例早期喉癌患者的临床资料，分析术后近期疗效和远期结局。结果：186 例 TisN M ～T N M 期声门型及声门上型喉癌患者的3 年总生存率为96.3% ，局部控制率为87.7% ，局部复发率为 0 0 3 0 0 3.7% ；5 年总生存率为92 .0% ，局部控制率为77.8% ，局部复发率为22 .6% ；淋巴结转移率为9.1% 。结论：CO2 激 光微创手术治疗早期声门型及声门上型喉癌的近期疗效和远期结局均较好，并可保留喉功能；而在中晚期喉癌和 声门上型喉癌患者中应慎重选择CO2 激光微创手术。 [关键词]　喉癌；早期；CO2 激光微创手术；治疗结果 [中图分类号]　R739.65 [文献标志码] A [文章编号]　1000-7431 (2013) 10-0909-05 Efficacy of transoral CO laser microsurgery for early laryngeal cancer 2 GAO Shu-feng, ZHANG Shao-rong, LIU Yue-hui, YANG Chun-ping, LUO Ying Department of Otorhinolaryngology-Head and Neck Surgery, Second Affiliated Hospital, Nanchang University, Nanchang 330006, Jiangxi Province, China [A BSTRACT]　Objective: To explore the efficacy of transoral CO2 laser microsurgery in patients with early laryngeal carcinoma. Methods: Total of 186 patients with stages TisN M -T N M glottic or supraglottic 0 0 3 0 0 laryngeal cancer between April 2003 and April 2008 were retrospectively collected. All of these patients received CO2 laser microsurgery. The clinical records and the follow-up information were analyzed. Results: The overall 3-year survival rate was 96.3%, 3-year local control rate was 87.7%, and 5-year local recurrence rate was 3.7%; the overall 5-year survival rate was 92.0%, 3-year local control