螺旋CT测量牙槽突裂植骨量可行性探究.doc

螺旋CT测量牙槽突裂植骨量可行性探究【摘要】目的:应用螺旋CT测量不规则山羊下颌骨块,探讨CT测量牙槽突裂植骨量的可行性。方法:取山羊下颌骨,修整为大小不同不规则的22块骨标本,分别用量筒水实测法以及CT层面描记计算法进行测量,进而对两种不同方法的测量结果进行统计学分析。结果: 以量筒实测的22块山羊下颌骨标本体积范围从0.9cm3到4.1cm?3,平均2.58cm?3;以CT测量的体积范围从1.1cm?3到4.0cm?3,平均2.56cm?3。两组数据间无显著差异。结论: 以描记CT扫描图像计算面积,进而计算骨体积的CT测量方法,经实验证明是准确的、可行的。 【关键词】螺旋CT;牙槽突裂 【中图分类号】782.2 【文献标识码】A 【文章编号】1008-6455(2010)08-0374-02 The available study of applicatingComputed Tomography (CT) to the evaluation of bone formation after alveolar bone grafting Song Yu?1 Liu Yanling?2 Li Tao?1 【Abstract】Objective:The purpose of this study was to discuss the application of Computed Tomography (CT) to the evaluation of bone formation after alveolar bone grafting (ABG). Methods: Two goat mandibular bones were broken up into 22 bone pieces in different size and irregular shape. Measuring cylinder was used to measure the volume of these bone pieces, and CT scans was used to calculate the same bones. The measurement result to two kinds of distinct means is carried on the statistics analysis. Results: The range of the volumes of the 22 pieces of the goat mandible got with measuring cylinder was from 0.9 to 4.1 cm?3, with a mean of 2.58 cm?3; The mean volume calculated from the CT scans was 2.56 cm?3 with a range of 1.1 to 4.0 cm?3. Statistical analysis was performed using the paired t-test and regression analysis. Conclusion:The method used to calculate the volume of the alveolar grafted bone by tracing out the bone area from CT scans proves to be feasible. 【Key words】Dimensional CT;Alveolar cleft 唇腭裂治疗已经由单纯关闭裂隙发展到综合序列治疗,牙槽突裂的治疗作为唇腭裂序列综合治疗重要的一个环节,已经越来越引起人们的重视。以自体骨移植治疗牙槽突裂成为现在临床上的主要治疗方法。但是国内外在手术时间,供骨区的选择等方面仍然存在争议,因此需要有一个能够准确、全面评估术区移植骨质量的方法,从而正确评价临床效果。上颌骨解剖与相邻组织结构比较复杂,牙槽突裂的裂隙和植入骨的三维形状非常不规则,而且没有明显清晰的边界,因此直接测量裂隙及植入骨的体积比较困难。近年来,已有不少研究使用螺旋CT对牙槽突裂植骨手术的疗效进行观察评价,效果较好,但是相关应用CT测量的骨体积与实际数值差距的报道却少见。 1 资料和方法 1.1 实验动物选择:本实验动物为2只本地成年山羊,14-16月龄,体重分别为19.1,24.5Kg。所用实验山羊由上海第二医科大学附属第九人民医院动物实验室统一购入管理及喂养。 1.2 牙槽骨模型的制备:处死山羊,切取其下颌骨,去除附着的软组织,拔除所有牙齿。使用医用高速涡轮