阻塞型睡眠呼吸暂停低通气综合征与脑卒中的临床特征与关系分析.docVIP

阻塞型睡眠呼吸暂停低通气综合征与脑卒中的临床特征与关系分析 中文摘要 目的：脑卒中已成为影响人类健康的最严重慢性病之一，具有突发性和严重性的特点，存在明显的三高（发病率高、致残率高、死亡率高）现象，越来越多的证据显示阻塞型睡眠呼吸暂停低通气综合征为脑卒中的独立危险因素。本研究比较急性脑梗死合并阻塞型睡眠呼吸暂停低通气综合征和不合并阻塞型睡眠呼吸暂停低通气综合征的急性脑梗死患者，血糖、血脂、肝肾功能、超敏C反应蛋白、电解质、凝血功能、血液流变学检查、身体质量指数睡眠呼吸暂停低通气指数美国国立卫生研究院卒中量表CS比例均高于无阻塞型睡眠呼吸暂停低通气综合征组患者，而OE、UE比例均低于无阻塞型睡眠呼吸暂停低通气综合征组患者。阻塞型睡眠呼吸暂停低通气综合征组患者的总胆固醇甘油三酯密度胆固醇低密度胆固醇Abstract Objective: Stroke?has become?one of the most?serious chronic diseases?to human health,?has the?characteristics of sudden?and serious,?there are obvious?three high?(high incidence rate, high disability rate,?high mortality)?phenomenon,?more and more?evidence of?obstructive sleep apnea hypopnea syndrome?is an independent?risk factor for stroke.?This study compared the acute cerebral infarction complicated with?obstructive sleep apnea?syndrome?and?obstructive sleep apnea?hypopnea syndrome in patients with acute cerebral infarction?with low?syndrome, blood glucose and blood lipid,?liver and kidney function,?high sensitive C reactive?protein, electrolytes,?blood coagulation?function,?blood rheology?examination,?BMI,?AHI, NIHSS score, Essen score?the difference,?CISS packet,?and analyze its correlation with the?clinical indexes between,?to investigate the?acute cerebral infarction complicated with?obstructive sleep?apnea hypopnea?syndrome?patients.?In addition，and further?study and analysis of?acute cerebral infarction complicated with?obstructive sleep apnea?hypopnea?syndrome?clinical features. Methods: In our prospective observational study, the?patients of acute cerebral infarction with?neural?Department of internal medicine in our hospital?ward?consecutively admitted,?agree and?can?cooperate to do?night polysomnography?(polysomnography,?PSG)?of 160 cases of?monitoring. According to whether the?obstructive?sleep apnea hypopnea?syndrome?patients were divided into?obstructive sleep apnea hypopnea?syndrome?group 106 cases,?male 61 cases,?female 45 cases,?mean age(58.87?+ 12.65). Among them, stroke patients with?mild