弹状病毒基质蛋白(matrix protein) 的研究进展 - 福建农业学报.pdf

福建农业学报26( 1) : 130~ 134, 2011 : 1008- 0384 (2011) 01- 130- 05 F uj ian Journal of Ag ricultural Sciences (M atrix protein) 1, 2 2 2 2 杨振慧 , 葛均青 , 龚 晖 , 林天龙 ( 1. , 350108; 2. , 350003) : 1 RNA , 5 , ( N cleoprotein, N) (Phosphoprotein, P) ( Matrix protein, M) ( Glycoprotein, G) RNA ( RNA polymerase, L) , ( M) , , , , M : ; ; ; ; : S 917, S941 : A Advances in research on rhabdovirus matrix protein 1, 2 2 2 2 YANG Zhenh i , GE J nqing , Gong H i , LIN T ianlong (1. Dep artment of Lif e Science, Fuj ian Normal University , Fuzhou, Fuj ian 350108, China; 2. Institute of iotechnology , Fuj ian A cademy of Agricultural Sciences, Fuz hou, F uj ian 350003, China) Abstract: Rhabdovir s contains a linear, negat ivesense and singlestranded RNA genome. It encodes 5 str ct ral proteins, incl ding n cleoprotein ( N) , phosphoprot ein ( P) , matrix protein ( M ) , glycoprot ein ( G) and RNA polymerase ( L) . The mat rix protein takes m ltif nction in the vir s infection cycle, incl ding participating in vir s b dding and assembly, inhibiting prot ein n cleocytoplasmic transport, and reg lating host gene transcription and ind cing cell apopt osis. Recent advances in the research on the mat rix protein are reviewed. Key words: rhabdovir s; matrix protein; str ct re; f nction; application , : , ICT V , 6 , 2 , ( Vesiculovirus) ; , [ 3] ( Lyssav irus ) RNA , ( Ep hemerovirus ) 5 , ( N cleoprotein, ( N ovirhabd