聚眈胶亲和膜包对透析液中内毒素去除的研究 - 大连医科大学学报.pdf

大连医科大学学报 Vol.30 No.1 第30 卷第 1 期 Feb.2∞8 2∞8 年2 月 Journal of Dalian Medical University 聚眈胶亲和膜包对透析液中内毒素去除的研究 王洪刚马丽红2 汤新强潘明臣1 (1.大连医科大学第一临床学院临床药学教研室，辽宁大连 11ω11; 2. 中国人民解放军210 医院临床药学教研室，辽宁大连 11ω11) 摘要: [目的]研究聚航滕亲和膜包对透析液中内毒素的去除。[方法]用堂试剂法测定透析液中内毒素。[结果] ①随着流速的增加，内毒素去除率有所下降。②温度对水溶液中内毒素的去除影响不明显。③含白蛋白透析液中内 毒素的去除率较低。[结论]聚耽膝亲和膜包可有效去除透析液中内毒素，且可较高的保留各种物质的有效成分。 关键词:聚耽牍亲和膜包;透析液;内毒素 申固分类号:R 94 文献标识码:A 文章编号: 1671 - 7295 ( 2∞8)01 -∞25 -04 Study of endotoxin removal in kidney dialysis solution by amide membrane package WANG Hong - gang 1 , MA Li - hong2 , TANG Xing - qiang 1 , PAN Ming - chen 1 (1 Depαrtment 01 Clinical Phαrmacy ， the First Affiliαted Ho伊tal 01 Dalian Medical University , Dalian 116011 , China;2 Depαrtment 01 Clinical Pharmacy , the 210 Hospital 01 the PLA ，V，αlian 116011 , Chinα) Abstract: [Objective ] To study the endotoxin removal in dialysis solution by amide membrane package. [ MethodsJ Deter- mination TAL (Tachypleus Amebocyte Lysate) endotoxin in dialysis solution. [Results ](With the increase of velocity , endotoxin removal rate has declined. ( Temperature on endotoxin in aqueous solution is not obvious impact of the removal. ( In albumin dialysis solution containing endotoxin removal rate is lower. [Conclusion ] The amide membrane package may effectively remove the endotoxin of dialysis fluid , also may the higher retention each kind of matter effective component. Key words: amide membrane package; kidney dialysis solution; endotoxin 海洋生物制品有限公司) ;堂试剂 (0. 03 EU/mL，批号