μ阿片受体a118g基因多态性对芬太尼静脉自控镇痛恶心呕吐的影响.docVIP

μ阿片受体A118G基因多态性对芬太尼静脉镇痛恶心呕吐的影响 袁静静 张卫 郑州大学第一附属医院麻醉科 【摘要】目的 观察μ阿片受体A118G基因多态性对妇科患者全麻术后芬太尼静脉镇痛恶心、呕吐的影响。20～50ASAⅠ或Ⅱ级。静脉注射咪、瑞芬太尼、异丙酚琥珀胆碱瑞芬太尼异丙酚，阿曲库铵术后芬太尼静脉自控镇痛-限制性片断长度多态性(PCR-RFLP)技术检测A118G基因多态性，根据基因型将病人分三组。ZHANG Wei, YUAN Jing-jing，KAN Quan-cheng, et al. Department of Anesthesiology，First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052,China 【Abstract】Objective: To evaluate the of OPRM1 A118G genetic polymorphism on postoperative nausea and vomiting induced by fentanyl intravenous analgesia in Chinese gynaecologic patients. Method: One hundred and sixty-five patients, aged 20-50 y