代谢综合征并中风的临床调研和其病机与证候研究.pdfVIP

提 要 目的：分析MS、中风相关的危险因素，在此基础上进一步探讨MS导致中风发病 的病机及证候规律，为中风防治研究提供新思路。方法：通过梳理 MS、中风的古今 文献，采集MS、中风患者的临床信息，运用t检验、卡方检验、Logistic回归分析， 分析相关危险因素、症状体征及中风病证候，结合中医理论初步探讨 MS 导致中风发 病的病机及其证候规律。结果：年龄增长、性别差异、饮食偏好、吸烟、饮酒、感受 压力大、情绪急躁、缺乏运动、打鼾，以及先天禀赋、家庭生活方式的沿袭等是促进 MS 痰热形成的危险因素，MS 能促使中风发病年龄提前，MS 中风、中风非 MS 各证候 间差异无统计学意义，中风病风痰火亢证比例最高，占 46.5%。舌脉对 MS 痰热证辨 证至关重要。结论：痰热是MS、中风重要的病理因素，痰热化火生风是MS中风的病 机关键，痰热证是 MS、中风最主要的证候，痰热证后期常转变为风痰瘀阻、阴虚风 动及气虚血瘀证。痰热体质是 MS、中风的易感体质。临床上要善于发现 MS，积极寻 找促使痰热形成的危险因素，及时地干预，防治结合，对延缓中风发病、防止中风复 发意义重大。 关键词 代谢综合征；中风；临床调研；病机；证候研究 Clinical，Pathogenesis and Syndrome Investigation of the Relationship between Metabolic Syndrome and Stroke StrokeSpecialty: Department of internal neurology of TCM Author: Qi Yingmei Tutor: prof. Ding Yuanqing Abstract Obejective:We analyzed the risk factors relative to MS and/or stroke,on the basis of which we further investigated the pathogenesis and syndrome rules of stroke caused by MS,in order to provide a new way of prevention and treatment of stroke.Method:We collected the clinical information of MS and/or stroke patients,used statistical methods such as t-test, chi-square analysis and Logistic regression etc. to analyze the relative risk factors,symptoms,physical signs and syndromes,primarily explored the pathogenesis and syndrome rules with referrance to TCM theories.Result: 1.aging, gender, diet hobby, smoking, drinking, mental tention, irritability, less sport exercise, snoring, as well as congenital disposition and life style etc. are risk factors which can promote the formation of phlegm-heat syndrome;2.MS patients would develop to stroke earlier than those without MS on average;3.Of the ms and stroke patients,phlegm-heat syndrome is