低分子肝素对中医各型IIP的临床疗效的视察.pdfVIP

提 要 目的：低分子肝素对肺肾两虚和痰热瘀阻型IIP的临床干预作用及安全性分析。 方法：入选肺肾两虚和痰热瘀阻型的 IIP 患者各 50 例，各期随机分为对照组与 观察组，对照组给予强的松、多索茶碱治疗；观察组在对照组的基础上加用低分子肝 素注射液治疗，4 组疗程均为 28 天，观察临床治疗效果。 结果：观察组症状、体征、辅助检查等指标改善情况与对照组有差异，早期、 慢性迁延期与晚期各阶段观察组的改善情况之间存在着差异，差异均有统计学意义（P ＜0.05）。 结论：低分子肝素对于中医各型 IIP 均有干预作用，但是对于痰热瘀阻型的干预 作用优于肺肾两虚型，且不良反应少，安全性高。 关键词 低分子肝素；特发性间质性肺炎；肺肾两虚；痰热瘀阻；临床观察 1 Low Molecular Weight Heparin on TCM Clinical Efficacy of Various Types of Observation IIP Speciality：Clinical research on the respiratory system diseases between traditional Chinese medicine and modern medicine Author：Yan Min Tutor：Prof. Weilu Zhang Abstract Objective：Low molecular weight heparin on lung and kidney deficiency and Phlegm Stagnation Clinical Intervention Type IIP and Security Analysis Methods: The lung and kidney deficiency and Phlegm Stagnation selected type of IIP patients ， 50 patients were randomly divided into two phases of the control group and observation group and control group were given prednisone， Doxofylline treatment; observation group in the control group based on the use of low molecular weight hepatic injection for the treatment， 4 groups were 28 days of treatment ， observation of clinical effect. Results: Symptoms， signs ， laboratory examinations and other indicators to improve the situation is different with the control group ， the early and late chronic stages PERSISTING improvement in the observation group there are differences between the differences were statistically significant (P 0.05 ) Conclusion: The low molecular weight heparin for the Chinese intervention of various types of IIP have ， but for the intervention of phlegm stasis type is better than lung and kidney