加减小柴胡汤治疗糖尿病下肢血管病变的临床视察.pdfVIP

陕西中医学院 硕士学位论文 加减小柴胡汤治疗糖尿病下肢血管病变的临床观察 姓名：郝维宾 申请学位级别：硕士 专业：中医内科学 指导教师：裴瑞霞 2011-04 中文摘要 [目的]观察血糖、糖化血红蛋白、ABI指数及中医症候积分的变化情况，分 析加减小柴胡汤治疗 2 型糖尿病周围 血管病变的临床疗效。并探讨糖尿病周围 血管病变的病理机制，为临床治疗提供科学理论依据。 [方法]将60例2型糖尿病下肢血管病变患者随机分为治疗组(30例)和对照 组(30例);对照组采用控制血糖的糖尿病的基础治疗,治疗组在此基础上,加用加 减小柴胡汤。治疗 3 月后,观察 2 组血糖、糖化血红蛋白、ABI 指数及中医症候 积分的变化情况并做肝、肾功能检查，进行统计分析，判断疗效及用药安全性。 [结果]加减小柴胡汤组较对照组能有效改善患者血糖水平，降低患者糖化血 红蛋白含量，改善患者ABI指数，同时明显缓解患者糖尿病下肢血管病变引起的 相关症状。治疗前后患者的肝、肾功能无明显变化，具有良好的疗效和安全性。 [结论] 加减小柴胡汤对 2 型糖尿病下肢血管病变具有较好的临床疗效，能 有效改善患者血糖、糖化血红蛋白、ABI指数及中医症候。 [关键词]加减小柴胡汤；2型糖尿病;周围血管病变 To add and subtract small entrapement decoction in the treatment of diabetes clinical observation of the extremities vascular lesions Abstract [Objective] glucose, glycated hemoglobin, ABI index and the change points TCM symptoms, plus reduce the Bupleurum Decoction of type 2 diabetes the clinical efficacy of diabetic angiopathy. Diabetic peripheral v diabetic angiopathy and explore the pathological mechanism for providing scientific theoretical basis for clinical treatment. [Method] 60 atients with type 2 diabetes, peripheral peripheral were randomly divided into treatment group (30 cases) and control group (30 cases); control group were the basis for diabetes control blood sugar treatment group on this basis, plus Add reduced Chai Hu Tang. Month after treatment was observed 2 blood glucose, glycated hemoglobin, ABI index and the change points TCM symptoms and do liver and kidney function tests were analyzed to determine the efficacy and drug safety. [Results] Bupleurum Decoction plus reduced compared with the con