四君子汤加减配合常规疗法治疗脓毒症脾胃虚弱型胃肠功能障碍的疗效和预后评价.pdf

摘 要 目的：四君子汤加减配合常规疗法治疗脓毒症脾胃虚弱型胃肠功能障碍的疗效及 预后评价。 方法：在确立严格的诊断标准、纳入标准、排除标准和疗效评定标准的基础上， 采用随机、均衡、对照的原则，将50例合格受试对象分为治疗组25例，除常规治疗 外另给予四君子汤加减，水煎服，400ml ，早晚各温服 200ml，日一剂，对照组 25 例给予常规治疗加温水 400ml，早晚各温服 200ml，日一剂。疗程为 7 天，对比治疗 前后胃肠功能及 APACHE Ⅱ评分变化，比较两组疗效，继发 MODS 比例及病死率情况。 结果：两组病人胃肠功能障碍评分治疗后均下降，治疗组降低程度优于对照组 (p<0.05)两组比较有显著差异(p<0.05)。治疗组总有效率为 89%，对照组总有效率为 70%，;治疗组继发 MODS 比例为24%，对照组继发MODS 比例为64%，两组比较比较， 有显著差异(p<0. 05);治疗组病死率为 20%，对照组病死率为 56%，两组比较差异显 著(p<0. 05) . 结论：四君子汤加减配合常规疗法治疗脓毒症脾胃虚弱型胃肠功能障碍可以改善 患者胃肠功能，降低继发 MODS 及病死率。 关键词 四君子汤;脓毒症;胃肠功能障碍;MODS SI Junzitang Combined with routine therapy for the treatment of sepsis of spleen and stomach type gastrointestinal dysfunction and prognosis evaluation Speciality: Internal Medicine of TCM Author:Liu Jinpeng Tutor: Professor.Kong Li Abstract Objective:SI Junzitang Combined with routine therapy for the treatment of sepsis of spleen and stomach type gastrointestinal dysfunction and prognosis evaluation Methods: to establish strict diagnostic criteria, inclusion criteria, exclusion criteria and evaluation standards on the basis of using a randomized, balanced,, control principle, 50 cases of eligible subjects divided into Chinese medicine group 25 cases, in addition to conventional treatment to give the Si Junzitang, Water decoction 400ml, each morning and evening. Warm 200ml, a conventional agents, a group of 25 patients given routine treatment plus warm 400ml, sooner or later the warm 200ml, Japan agent. For a period of 7 days, compared before and after treatment of gastrointestinal function and APACHE Ⅱ score changes, compared the effect of two groups, secondary to mods ratio and mortality rate condition Results: the two gro