中药芪参复康对焦虑模型大鼠 ep及细胞因子的影响(The effect of the Chinese traditional Chinese medicine on the anxiety model and the influence of the ep and cytokines).docVIP
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中药芪参复康对焦虑模型大鼠 ep及细胞因子的影响(The effect of the Chinese traditional Chinese medicine on the anxiety model and the influence of the ep and cytokines)
中药芪参复康对焦虑模型大鼠 ep及细胞因子的影响(The effect of the Chinese traditional Chinese medicine on the anxiety model and the influence of the ep and cytokines)
Effects of Chinese traditional Chinese medicine and ginseng compound on beta ep and cytokines in rats with anxiety model
Article: /
[abstract] objective: to study the anti-anxiety effect of QSFK capsules? The mechanism of immunomodulation was preliminarily discussed. Methods: using the international common high gear cross maze model (epm) anxiety animal model, in contrast with the use of the styrocyclone (bus), to observe the beta of QSFK in the epm rats. Ep, serum no, il? 1 beta, il? Effect of 6 and TNF alpha. Results: compared with model group, QSFK and bus can reduce the plasma beta of epm rats. Ep content (p 0.01), for hypothalamic beta? No significant impact of ep levels; However, the serum no level (p 0.05) was increased in both groups. QSFK can also raise serum il of epm rats. 1 beta and TNF alpha, right? 6 content has no obvious influence; Bus does not change the serum cytokines level in rats with this anxiety model. Conclusion: QSFK reduces plasma beta? Ep content increases serum no concentration and epm serum il? 1 beta and TNF alpha level, to regulate the immune dysfunction of the body under anxiety.
[key words] qi shen fukang capsule, a cross maze model, beta endorphin nitric oxide cells due to subclass anxiety
0 the introduction
Stilbene and convalescent (qishenfukang, QSFK) capsule is the hospital clinical mainly used in the treatment of liver blood deficiency, blood not yangxin, heat within the virtual bother can not sleep cause of anxiety of prescription. The experimental results show that the past QSFK capsule can increase the animals spontaneous activities, enhance their strength, and can reverse forced swimming in cold water stress caused by the change of the content of adrenal vitc [1], and shown the anti-stress and anti-anxiety effects of the preparation. We adopt international general anxiety animal mo
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