酿酒酵母进级进化过程中的基因丢失现象初探.pdfVIP

7 2 生命科学研究 Vol.7 No. 2 2003 6 Life Science Researc June 2003 朱新宇 ( , 226007) : 酿酒酵母进级进化过程中的基因丢失问题很少被研究. 利用现有的蛋白 数据库, 通过设定判断标准, 预期可以获得更多这方面的案例以便进行相关问题的研究. 利用SMART 蛋白 域家族数据库, 根据在已完成测 序的7 种真核生物蛋白 域家族成员中存在或不存在酿酒酵母蛋白 域信号, 判断是否发生了基因丢失. 通过 这种方法, 共有6 个酿酒酵母基因判断为在进级进化过程中发生了丢失, 还探讨了这些基因发生丢失的可能 机制. : 酿酒酵母; 基因丢失; 关联进化 : Q559 : A : 1007-7847(2003) 02-0139-05 A Preliminary Research on the Gene Loss During Order Evolution of Saccharomy ces cerevisiae ZHU Xin-yu ( Dep artment of Lfi e Science and Technology ,Nantong Normal College ,Nantong 226007, Jiangsu, China) Abstract: T e problem of gene loss during order evolution of saccharomyces cerevisiae was less studied. It is anticipatable t at more t is type of cases will be found t roug setting criterion and using extant protein domain database. By using SMART database, t e genes lost during evolution (GLDE) were establis ed against t e presence absence of Saccharomyces cerevisiae protein domain signals in 7 reference species w ic ave been completely sequenced. Saccharomyces cerevisiae 6 geneswere considered as GLDEs, and t e possiblemec anisms resulting in t ese GLDEs were also discussed. Key words: Saccharomyces cerevisiae ;gene loss; correlated evolution (Lfi e Science Research , 2003, 7( 2) : 139~ 143) 10 , , (gene lost during evolution, GLDE) , ( p ylogenetic [ 1, 2] [ 3, 4] , marker)