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COPD的激素治疗(Hormone therapy for COPD)
COPD的激素治疗(Hormone therapy for COPD)
Acute exacerbation of COPD: treatment options for antibiotics and glucocorticoids
2015-02-27 16:39: da kayla font size - | +
The treatment of antibiotics and systemic glucocorticoid is an important link in the treatment of acute severe COPD (AECOPD). From the university of Colorado medical Kiser process and Vandivier two scholars wrote a review and summary reviewed recent new evidence of antibiotics and hormones in the treatment of AECOPD, and evaluate the different types of antibiotics and glucocorticoids dose influence on prognosis of patients, the article published in a recent issue of Curr Opin Pulm Med of the magazine.
The worlds 65m people suffer from chronic obstructive pulmonary disease (COPD), which kills more than three million people each year. The death rate from COPD is increasing, and the world health organization estimates that COPD will be the third leading cause of death by 2030. In the United States alone, there are 24 million COPD patients and $50 billion in annual treatment costs.
The AECOPD is defined as a symptom of an increased respiratory syndrome that exceeds the daily variation and needs to change the acute onset of the medication. Because of AECOPD will cause the change of lung function, and takes a few weeks before the onset of to return to the state, reduce the patients quality of life, thus accelerating the lung function decline, AECOPD in COPD is most severe in many types of adverse events.
Severe AECOPD is characterized with respiratory failure requiring hospital treatment combined hypoxemia, admitted to the hospital because of AECOPD patients each year in the United States to 715000 person-time, need for mechanical ventilation AECOPD patients admitted to hospital mortality of about 15% to 15%.
Therefore, it is necessary to improve the prognosis of patients with AECOPD through treatment intervention. In addition to oxygen therapy and short-acting bronchodiastolic, systemic glucocorticoids and antibi
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