补阳还五汤加减治疗左心相关性肺循环高压气虚血瘀证的临床探究.pdfVIP

提 要 目的：应用益气活血、化痰逐瘀法，以补阳还五汤加减治疗左心相关性肺循环高 压气虚血瘀证患者，观察其临床疗效，以验证从气虚血瘀论治左心相关性肺循环高压 的临床可行性，探讨左心相关性肺循环高压中医辨证思路与治疗，发掘中医药治疗左 心相关性肺循环高压的新思路及方法。方法：选取符合标准的病例 60 例，随机分为 治疗组和对照组各 30 例。治疗组予常规西药治疗，加用补阳还五汤加减水煎服日一 剂，对照组予常规西药治疗。两组均治疗4周为1疗程，连续治疗3个疗程后判定临 床症状、六分钟步行试验及超声心动图变化。结果：中医综合证候总有效率治疗组 90.0%，对照组 66.7%，治疗组优于对照组（R 治疗 R 对照 ）；同时治疗组临床症状、六 分钟步行实验和超声心动图肺动脉高压情况也较对照组明显改善。结论：加用具有益 气活血、化痰逐瘀作用的补阳还五汤加减比单纯西药治疗更能明显改善患者临床症 状，提高患者运动耐量和降低肺动脉收缩压，从而改善由于冠心病导致的左心相关性 肺循环高压的预后和治疗。 关键词 左心相关性肺循环高压；气虚血瘀证；临床研究 The clinical research about plus-minus of Buyang Huanwu Decoction treating the type of left heart relevant pulmonary hypertension Speciality：Cardiopathy Author ：Feng Jikang Tutor：Professor Cao Bin Abstract Objective：Through application of supplement qi and activate blood circulation, resolving phlegm and blood stasis methods, observe the clinical curative effect of Buyang Huanwu Decoction curing the left heart relevant pulmonary hypertension patients. And verify its clinical feasibility in treating qi deficiency to blood stasis type patients. In addition, investigate the TCM differentiation ideas and treatments for curing the left heart relevant pulmonary hypertension and excavate new ideas and methods of the TCM therapy for left heart relevant pulmonary hypertension. Methods ：Select 60 patients complied with standards and divide them into treatment group and control group randomly with thirty patients respectively. Give the treatment group conventional western medicine therapy and the plus-minus of Buyang Huanwu Decoction, decocting and taking a dose one day. Give the control group conventional western medicine treatment. Treat both groups 4 weeks as a period of treatment and three periods continuous. After