辨病辨证相结合治疗膝骨关节炎临床视察.pdfVIP

提 要 目的：通过观察治疗前后两组膝骨关节炎患者疗效性及安全性指标的变化情况， 探讨辨病辨证相结合的方法治疗膝骨关节炎的临床疗效。方法 ：本试验统计自 2009.3～2010.11 门诊及病房的膝骨关节炎患者 60 例，随机分为治疗组和对照组各 30 例，治疗组选用中医辨病辨证中药治疗方案，对照组选用西药贝速清治疗方案， 服药2个月，观察两组治疗前后膝骨关节炎疗效指标、中医证状积分指标、实验室检 查指标、安全性指标等。结果：治疗后，两组在治疗总有效率、中医证侯疗效方面无 显著性差异（P0.05）；两组患者治疗前后症状积分方面，有显著差异（P0.01），治 疗后组间比较，行走疼痛及活动受限症状积分有显著差异（P0.05）；两组患者治疗 前后 CRP 有显著差异（P0.01），治疗后组间比较无显著性差异（P0.05）。结论： 辨病辨证相结合的思路治疗膝骨关节炎取得良好疗效，并有较好的安全性。 关键词 膝骨关节炎；辨病辨证相结合 Clinical Observation on knee osteoarthritis with Treatment Based on Combination of Disease and syndrome differenciation Speciality ：Internal medicine of TCM ， The study of Rheumatic immune diseases Author ：Li Tao Tutor ：Professor Song Shaoliang Abstract Objective: evaluate the clinical efficacy and safety of TCM treatment based on the combination of disease and syndrome differenciation , by comparing curative effect and safety indexes between the treatment group and control group. Methods: collect 60 patients from clinics and wards from 2009.3 ~ 2010.11. The patients were randomly assigned into two groups. 30 in the treated group treated with Chinese herb and 30 in the control group treated with western medicine. After 2 months , we observe the varieties of indexes such as the total efficacy index , the syndrome credits, C-reactive protein (CRP) as well as safety indexes. Results: after the clinical observation of the two groups there is no significant differences between the total efficiency and syndrome indexes(P 0.05); there are significant differences in the two groups with syndrome credits before and after treatment, (P 0.01), inter-group comparison after treatment in walking pain and arising pain has significant differences in synd