雷公藤多甙片合益肾蠲痹丸治疗类风湿关节炎的疗效评价.pdfVIP

提 要 目的：通过临床观察评价雷公藤多甙片联合益肾蠲痹丸治疗类风湿关节炎肾虚血 瘀证的临床疗效。 方法：选择2010年4月～2011年4月就诊于山东中医药大学附属医院风湿科门 诊及住院患者。将符合纳入标准的 80 例患者随机分为试验组 40 例和对照组 40 例， 试验组服用雷公藤多甙片和益肾蠲痹丸，对照组服用甲氨喋呤和柳氮磺吡啶片，两组 治疗时间均为24周，观察两组的关节压痛个数、关节肿胀个数、晨僵时间、血沉（ESR）、 C反应蛋白（CRP）等指标的变化，以及临床疗效比较。 结果：试验组能明显改善患者症状，对临床症状、实验室检查、中医证候的改善 明显优于对照组。 结论：雷公藤多甙片联合益肾蠲痹丸能明显改善患者病情，治疗效果优于甲氨喋 呤与柳氮磺吡啶片。 关键词 关节炎，类风湿，雷公藤多甙片，益肾蠲痹丸，临床疗效。 Tripterygium wilfordii much glucoside pieces and benefiting kidney Juan bi pill certified share treatment evaluation of clinical curative effect of rheumatoid arthritis Speciality：Internal Medicine of T.C.M Rheumatic Diseas Author：Sun Qian Tutor：Professor.Sun Su Ping Abstract Objective: To observe the clinical evaluation tripterygium wilfordii much glucoside pieces and benefiting kidney Juan bi pill certified share treatment rheumatoid arthritis kidney blood stasis syndrome of clinical curative effect.Method: Choose in April 2010 to April 2011 clinic in Shandong university of Traditional Chinese Medicine hospital Rheumatism Department outpatient and inpatient. Will meet the criteria 80 cases were randomly divided into the test group (40 cases) and control group (40 cases) , patients tripterygium wilfordii of more glucoside and benefiting kidney Juan bi pill, the control group taking methotrexate and liu nitrogen of sulfonylurea pyridine, two groups of treatment time for 24 weeks are observed, the two groups of joint tenderness number, joint swelling number, time of morning stiffness , ESR, CRP, and other indicators, and the change of the curative effect of traditional Chinese medicine and