同型半胱氨酸、胱抑素c 水平与高血压病及高血压 - 中国动脉硬化杂志.pdf

CN43鄄1262/ R摇 中国动脉硬化杂志2014年第22卷第5期 495 [文章编号]摇 1007鄄3949(2014)22鄄05鄄0495鄄04 ·临床研究 · 同型半胱氨酸、胱抑素C水平与高血压病及 高血压脑出血的相关性 孙 玙,杨水泉 (佛山市三水区人民医院神经内科,广东省佛山市528100) [关键词]摇 同型半胱氨酸;摇 胱抑素C;摇 高血压病;摇 高血压脑出血 [摘摇 要]摇 目的摇 研究同型半胱氨酸、胱抑素C与高血压病及高血压脑出血的相关性。 方法摇 将研究对象分为高 血压脑出血组(108例)、单纯高血压组(100例)和正常对照组(100例),检验其血中同型半胱氨酸、胱抑素C、总胆 固醇、甘油三酯水平。 结果摇 高血压脑出血组及单纯高血压组同型半胱氨酸、胱抑素C水平高于正常对照组,差异 有统计学意义(P0.05)。 高血压脑出血组同型半胱氨酸、胱抑素C水平高于单纯高血压组,差异有统计学意义 (P0.05)。 同型半胱氨酸、胱抑素C与总胆固醇、甘油三酯均无相关性(P 0.05)。 结论摇 监测同型半胱氨酸、 胱抑素C水平对早期防治高血压及脑出血有重要意义。 [中图分类号]摇 R741 [文献标识码]摇 A Correlative Research Between Homocysteine,Cystatin Cand Patients with Essential Hypertension and Hypertensive Intracerebral Hemorrhage SUN Yu,and YANG Shui鄄Quan (Department of Neurology,SanshuiDistrict People爷s Hospital of Foshan City,Foshan,Guangdong 528100,China) [KEY WORDS]摇 Homocysteine;摇 Cystatin C;摇 Essential Hypertension;摇 Hypertensive Intracerebral Hemorrhage [ABSTRACT]摇 摇 Aim摇 To investigate the correlation between homocysteine (Hcy),cystatin C (Cys C) and patients with essential hypertension and hypertensive intracerebral hemorrhage.摇 摇 Methods摇 Subjects were divided in to hyper鄄 tensive intracerebral hemorrhage group (108 cases),essentialhypertensiongroup (100 cases)andcontrol group (100 ca鄄 ses),andtheircystatinC,homocysteineandtotalcholesterol (TC)andtriglycerides (TG)weresurveyed.摇 摇 Results摇 The patientswithhypertensiveintracerebralhemorrhageandessentialhypertensionhadhigherlevelsof Hcy and CysCthan the controlgroup (P0郾05).摇 Thepatientswithhypertensiveintracerebralhemorrhagehadhigherlevelsof HcyandCysC than the essential hypertension group (P0郾05).摇 Therewas no correlation betw