正常高值血压者颈动脉弹性改变的初步观察及其roc分析 - 中华医学会.docVIP

硬度指数脉搏波速度正常血压高值者弹性 阚艳敏马琳 刘洋 李建【摘要】 目的 应用血管回声跟踪技术观察正常血压高值者颈动脉弹性硬度指数（β）脉搏波速度（PWVβ）。方法 二维超声测量正常血压高值76例与正常对照组50例双侧颈动脉内中膜厚度（IMT），并应用ET技术检测动脉βPWVβ，对比分析；运用ROC分析法进行统计学分析。结果 β、PWVβ对照组增高（P0.001）（P 0.05）；ROC分析β、PWVβ和股动脉β、PWVβ的曲线下面积分别为0.762、0.8610.778、0.891，以β 7.45、PWVβ 6.05m/sβ7.55、PWVβ6.15m/s作为正常高值者动脉弹性异常的诊断界值时，敏感度与特异度均较高。结论 正常血压高值者的动脉弹性在内中膜未出现形态学改变前已经降低，β 7.45、PWVβ 6.05m/sβ7.55、PWVβ6.15m/s能够作为正常高值者动脉弹性异常的诊断界值。 【关键词】动脉；动脉弹性；正常血压高值；血管回声跟踪技术 Evaluation of peripheral artery elasticity in prehypertensive people by β and PWVβ Kan Yan-min, Ma Lin, Liu Yang, Liu Shui-peng, Li Jian, Wang Yi-hua (Department of Ultrasound, Affiliated Hospital of North China University of Science and Technology, Tangshan, 063000, China) Abstract: Objective To observe the carotid artery and femoral artery elasticity in prehypertensive people by echo tracking technique (ET), and investigate the value of β and PWVβ in evaluation of peripheral artery elasticity. Methods Bilateral carotid artery intima-media thickness (IMT) was measured by two-dimensional ultrasound in 76 subjects with prehypertension and 50 subjects of normal control group, using ET detected carotid artery elastic β and PWVβ, and two sets of parameters were comparative analyzed. ROC analysis was used for statistical analysis. Results Compared with the normal controlled group, β and PWVβ were increased in subjects with prehypertension (P0.001), IMT in?the?two?groups?no?significant?difference (P0.05). ROC analysis showed that the area about β and PWVβ of carotid artery and femoral artery under the curve respectively were 0.762, 0.861, 0.778, 0.891, while β 7.45 and PWVβ 6.05m/s of carotid artery, and β 7.55 and PWVβ 6.15m/s of femoral artery as diagnosis amputation value of carotid artery elastic anomaly in prehypertensive people, sensitivity and specificity were higher. Conclusions The carotid artery elasticity have reduced before the artery IMT did not appear morphological change, β 7.45 and PWVβ 6.05m/s of carotid artery, and β 7.55 and P