4 缺氧（4 hypoxia）.doc

4 缺氧（4 hypoxia） Five hypoxia Hypoxia (hypoxia) is an abnormal change in the function, metabolism, and morphology of the organism, or even life-threatening, when oxygen supply is inadequate or the tissue is oxygen deficient, called hypoxia. Hypoxemia: the lack of oxygen in the arteries results in an inadequate oxygen supply to the tissue (1) common blood oxygen index and its significance; Tissue oxygen supply = arterial oxygen content * tissue blood flow Tissue oxygen consumption = (arterial oxygen content, venous oxygen content) * tissue blood flow 1. oxygen partial pressure (partial, pressure, of, oxygen, pO2) PO2 refers to the tension produced by the oxygen molecules dissolved in the plasma in the physical state. Normal value: paO2=, 100mmHg, pvO2=, 40mmHg The level of paO2 depends on the oxygen partial pressure and the external respiratory function of the inhaled gas. It is also the dynamic factor of the diffusion of oxygen into the tissue PvO2 reflects the state of internal respiratory function, which can affect oxygen content and oxygen saturation 2. oxygen capacity (oxygen, binding, capacity, cO2max) CO2max refers to paO2, 150mmHg, paCO2, 40mmHg, and 38 DEG C, the maximum amount of oxygen that Hb can combine in 100ml blood. Normal value: 8.92mmol/L The level depends on the amount and quality of Hb in the blood, reflecting the capacity of the blood to carry oxygen 3. oxygen content (oxygen, content, cO2) CO2 is the amount of O2 actually contained in the blood of 100ml. The oxygen dissolved in the plasma by the physical state and the two component of the oxygen bound to the hemoglobin. Normal value: caO2:19ml% cvO2:12~14ml% Depends on the quality and quantity of paO2 and hemoglobin, The caO2 can reflect the oxygen supply of the blood to the tissues; cvO2 is related to the ability of the tissue to utilize oxygen 4. oxygen saturation (oxygen, saturation, sO2) SO2 refers to the degree of binding of Hb to oxygen, the percentage of the actual combined oxygen content