胃食管反流病的发病机制与中医辨治规律初探（Study on the pathogenesis of gastroesophageal reflux disease with Chinese Medicine）.docVIP

胃食管反流病的发病机制与中医辨治规律初探（Study on the pathogenesis of gastroesophageal reflux disease with Chinese Medicine） Study on the pathogenesis of gastroesophageal reflux disease with Chinese Medicine Update Date: 2009-04-19 click: King Yang Jinguowang king Yan Gang Keywords gastroesophageal reflux disease; pathogenesis; TCM syndrome differentiation; CLC number: R 256.3, document identification code: A, article number: 1007-5615 (2000) 02-0005-02 Gastroesophageal reflux disease (GERD) is too much stomach and duodenal contents into the esophagus caused by heartburn, acid reflux symptoms, and can lead to tissue outside the oropharynx, larynx, esophagus and esophageal airway damage etc.. The incidence of the disease in the western countries is about 7 to 15%. Although there has been no epidemiological investigation in our country, the incidence is not low. [1] the pathogenesis of this disease has not been very clear. Most of that damage factor can not be effectively removed by reflux, or weaken the anti reflux mechanism can not curb the regurgitation into the esophageal cavity, which can lead to the occurrence of GERD. The lower esophagus expanded muscle (LES) is the first barrier for anti reflux [2], and plays an important role in the portal. When LES continues to relax or LES is over relaxed, both can cause reflux, while the former is spontaneous reflux, and GERD patients have up to 60 to 70% TLESR (LES transient relaxation). Accompanied by acid reflux [3, 4]. Normal people also have stomach - esophageal reflux, but only a handful of people suffering from reflux esophagitis in 2, the main second, third barrier and esophageal lumen clearance mechanism and instant esophageal mucosa barrier anti reflux effect is closely related. When the two barrier removal of reflux in damage factor (such as H+, pepsin, trypsin, bile salt reduction, etc.) or the reflux material increase, can not effectively prevent or neutralize the damage factor, damage factor in esophageal mucosa, which cause hea