安心颗粒对心梗死大鼠血清no、nos含量和其血管新生影响的实验研究.pdf

口 罩 曰 冰 中英文缩略词汇表···········。·································3 中文摘要···········。·······················。·················4 英文摘要·····················································5 引‘5l 言·················。···································7吾 ·················。···································7 正 文······································-··············9 第一部分理论研究···········································9 1．我国中医学对冠心病的认识·-·································9 1．1；I高名溯；原·················································9 1．2；I高l因；I高机··················································9 1．3辨证分型·················································10 1．4治．疔原则······················．．·····················-····11 2．现代医学对冠心病的认识············．．········。·············12 2．1西医病因病机···，·········································12 2．2西医病理变化·······························-·············16 2．3西医治疗·················································17 第二部分实验研究·······，···。······························20 1．实验材料··················································20 1．1实验动物···············．．···一·一·一·．．．．．．-一··．．····一·20 1．2药物与试剂··················．．·．．，·一．．······一·．．·······20 1．3仪器与器械···············································20 2．实验方法··················································20 2．1实验动物模型制备·········································20 2．2技术路线与实验方案·····················。·················21 2．3统计分析方法·····················，·······················22 3．实验结果与分析····························。···············22 3．1各组大鼠心肌梗死面积的组间比较···························22 3．2各组大鼠血清NO及NOS含量的组间比较····················23 的组间比较··················································24 第三部分讨论·············································26 1．MI模型制备过程的常见问题与关键要点·······················26 2．NO及NOS在缺血性心肌病中的作用··························27 3．冠脉侧枝循环以及血管生成··································29 3．1冠状动脉侧枝循环································