ANALYTICAL DETECTION LIMIT GUIDANCE （分析检出限指导）.pdf

ANALYTICAL DETECTION LIMIT GUIDANCE Laboratory Guide for Determining Method Detection Limits Wisconsin Department of Natural Resources Laboratory Certification Program April 1996 PUBL-TS-056-96 introduction and background The Department of Natural Resources (DNR) formed a Technical Advisory Committee in November, 1990 at the request of the Secretary of the Department to examine the LOD/LOQ language in Ch. NR 106, Wis. Adm. Code, and the corresponding language in WPDES permits to determine if the permit language was consistent with the code, and if not, to formulate recommendations to achieve consistency. The committees report (WI DNR, 1994), issued on January 2, 1994, recommended implementing new, consistent permit language based upon scientific limitations. The report also addressed related LOD/LOQ issues facing the Department raised through the investigation but not directly within the Committees charge. These issues were deemed critically related to the LOD/LOQ issue and the Committee urged the Department to give serious consideration to implementing (these) recommendations. Among them: 1. The Department needs to provide permittees with guidance instructing them how to report, interpret and apply sampling results that are below the LOQ. 2. The Department needs to develop uniform definitions of LOD and LOQ which are applicable to all environmental sampling programs. The need for consistent definitions and low level data reporting across all of the agencys environmental programs compelled the Laboratory Certification Program, to play a significant role in coordinating the Departments efforts. The Laboratory Certification Code, Ch. NR 149, Wis. Adm. Code, which requires laboratories to statistically determine their detection limits