全血粘度影响因素多元线性回归研究.docVIP

全血粘度影响因素多元线性回归研究【摘要】 目的 探讨全血粘度与其影响因素的依存关系。方法 检测66例患者的全血粘度(低切、中切、高切)、血浆粘度、红细胞压积、红细胞聚集指数和红细胞变形指数,采用SAS进行多元线性回归分析。结果 低切全血粘度=0.083+8.067血浆粘度(0.481)+0.319红细胞压积(1.155)+4.310红细胞聚集指数(0.671)+17.867红细胞变形指数(1.047);中切全血粘度=19.120+ 4.297血浆粘度(0.498)+0.183红细胞压积(1.288)+1.435红细胞聚集指数(0.434)+9.433红细胞变形指数(1.074);高切全血粘度=9.625+2.532血浆粘度(0.482)+0.122红细胞压积(1.408)+6.033红细胞变形指数(1.129)。结论 对全血粘度的相对贡献,在低切情况下,以红细胞压积最大,其次为红细胞变形指数、红细胞聚集指数和血浆粘度;在中切情况下,以红细胞压积最大,其次为红细胞变形指数、血浆粘度和红细胞聚集指数;在高切情况下,以红细胞压积最大,其次为红细胞变形指数和血浆粘度,红细胞聚集指数对其无明显影响。对全血粘度增高或降低患者,治疗过程中宜同时考虑上述影响因素及其相对贡献的大小。 【关键词】 全血粘度;影响因素;血液流变学;多元线性回归分析 Theanalysisofmultiplelinearregression onthe factorsaffectting bloodviscosity Dong Yujiang,Chen Shouqiang. Department of Cardiology,the Second Affiliated Hopital of Shandong Chinese Medicine College,Shandong 250001,China 【Abstract】 Objective To study dependent relationship on blood viscosity and the factors affectting it. Methods Multiple linear regression was adopted to analyze 66 patientss blood viscosity (at 10s1,351 and150s1, BV),plasma viscosity (PV),hematocrit (HCT),the index of erythrocyte aggregation (IEA) and the index of erythrocyte disfiguration (IED). Results BV(10s1)=0.083+8.067 PV(0.481)+0.319 HCT (1.155)+4.310IEA( 0.671)+17.867 IED (1.047);BV(35s1) = 19.120+4.297 PV(0.498)+0.183 HCT(1.288)+ 1.435 IEA(0.434)+9.433 IED(1.074) ;BV(150s1)=9.625+2.532 PV(0.482)+0.122 HCT(1.408)+ 6.033 IEA (1.129). Conclusion According to the standard cofficient of partial regression, the factor of maximum relative contributiom to BV was HCT,then was IED、IEA and PV at 10s1.The factor of maximum relative contributiom to BV was HCT,then was IED、PV and IEA at 35s1.The factor of maximum relative contributiom to BV was HCT,then was IEA and PV at 150s1.The factors affectting BV and their relative contribution should be considered at the same time while treating hyperviscosaemia or hypoviscosaemia. 【Key words】 Blood viscosity;The factors affectting blood viscosity;Hemorheology;Multiple linear regressio