莫沙必利联合氟哌噻吨美利曲辛片治疗胃肠功能紊乱.docVIP

莫沙必利联合氟哌噻吨美利曲辛片治疗胃肠功能紊乱[摘要] 目的:探讨促胃肠动力药莫沙必利与氟哌噻吨美利曲辛片合用对胃肠功能紊乱的临床疗效。方法:将胃肠功能紊乱患者70例分为A、B两组,分别给予促胃肠动力药莫沙必利加氟哌噻吨美利曲辛片或单纯给予促胃肠动力药莫沙必利口服。结果:莫沙必利加氟哌噻吨美利曲辛片与单纯给予莫沙必利治疗胃肠功能紊乱疗效比较,差异有统计学意义。莫沙必利加氟哌噻吨美利曲辛片能明显改善症状,而另一组症状改善不如联合用药组。结论:莫沙必利与氟哌噻吨美利曲辛片联合是治疗胃肠功能紊乱的一种较好方案。 [关键词] 胃肠功能紊乱;莫沙必利;氟哌噻吨美利曲辛片 [中图分类号] R573.5 [文献标识码]A [文章编号]1674-4721(2010)06(c)-030-02 Clinical research on gastrointestinal disorders treated by mosapride combination with flupentixol and melitracen tablets YANG Zhifeng (People’s Hospital of Zhongshan City, Guangdong Province, Zhongshan528403,China) [Abstract] Objective:To investigate the effect of treatment for gastroenteroathy using mosapride and flupentixol and melitracen tablets. Methods:Gastrointestinal disorders, 70 patients were divided into A, B groups,which were given oral gastrointestinal motility drug mosapride and flupentixol and melitracen tablets or simle gastrointestinal motility drug mosapride. Results:The differences in efficacy was significant with gastrointestinal motility drug mosapride and flupentixol and melitracen tablets or simple gastrointestinal motility drug mosapride. The mosaride and flupentixol and melitracen tablets could significantly improve symtoms. Another group of symtoms inferior to the combination group. Conclusion:It is a goodprogram to treat gastroenteroathy using mosapride combined with flupentixol and melitracen tablets. [Key words] Gastroenteroathy;Mosaride;Flupentixol and melitracen tablets 胃肠道功能紊乱,又称胃肠神经官能症,是一组胃肠综合征的总称,临床表现以持续性或反复发作性的胃肠道运动功能障碍为主,如连续性嗳气,咽部异物感,两肋和胃脘部的胀闷,串痛及胃内不适感,腹痛、腹胀、腹泻及便秘,常有排便不畅感或排便次数增加,粪便稀或干等症状。其病因和病理主要为三方面:①消化系统疾病,消化不良、胃溃疡、胃炎、急性胃肠炎。②饮食因素,不规律的饮食习惯。③精神心理因素,对于成年女性、脑力劳动者、性格内向者、常处于神经过敏状态的人等胃肠道功能紊乱易感人群。至今尚无肯定的治疗方法,目前很多学者认为与精神心理因素关系较为密切,因此对于精神心理方面的治疗成为治疗此种疾病的一项重要治疗措施。本文收集了70例患者的临床资料进行讨论。 1 资料与方法 1.1 一般资料 本组患者70例,年龄21～70岁,平均(39.3±4.6)岁;病程1～5年,平均18个月。随机分为两组,A组35例,其中,男18例,女17例;B组35例,男16例,女19例。两组患者的性别、年龄及病程比较差异无统计学意义。均符合以下诊断标准:①有下例症状之一项或数项,餐后饱胀感、嗳气、反酸、恶心、呕吐等;②有下列症状之一项或数项,腹痛、腹胀、腹泻或