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降钙素原(Procalcitonin)
English Name: procalcitonin
English abbreviations: PCT
PCT is a protein, it increased in the plasma level of bacteria, fungi and parasites when severe infection and sepsis and multiple organ failure. Autoimmunity, allergy and infection of PCT will not increase. Local bacterial infection, mild infection and chronic inflammation will not lead to the increase of. Bacterial endotoxin as a crucial role in the process of induction.
PCT reflects the degree of active systemic inflammatory response. The influence of PCT levels factors including infected organ size and type, the type of bacteria, the degree of inflammation and immune response status. In addition, PCT was a large minority of patients after surgery can be measured up to 1~4d.
The elevated PCT level in severe shock, systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), even without bacterial infection or bacterial disease. However, in these cases the PCT levels are usually lower than those in patients with bacterial disease. From the release of cytokine and intestinal bacterial translocation caused by induction.
Indications
PCT is a parameter for diagnosis and monitoring of bacterial infection in inflammatory diseases.
The determination of PCT can be predicted as:
As a parameter to the differential diagnosis of acute bacterial and non bacterial infection and inflammation.
Monitoring the risk of infection (such as immune suppression period, patients after surgery and organ transplantation after multiple trauma) and need intensive care patients, used to detect bacterial infection or systemic effects of detection of septic complications.
Evaluation of severe inflammatory disease clinical course and prognosis, such as peritonitis, sepsis, SIRS and MODS.
The serum PCT in various diseases of type
PCT increased PCT decreased or increased slightly
Bacterial infection with systemic inflammation, such as peritonitis, soft tissue infection of hepatitis B virus in
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