单核细胞（Monocyte）.docVIP

单核细胞（Monocyte） Monocyte Monocyte is the largest white blood cell. The nucleus is often offset, multiformity, such as oval, kidney shaped (a), horseshoe shaped (b) and irregular shape (c), often have a sense of folding (c); the chromatin is loose reticulate, lighter colored. Cytoplasm and basophilic, but azurophilic granules containing a large number of tiny and dyed gray blue particles containing peroxidase. Blood smear, Giemsa staining. Catalog 1. brief overview The 2. main purposes 3. structural characteristics 4. clinical cases A brief overview Mononuclear cells derived from bone marrow hematopoietic stem cells in the bone marrow, and development. When they enter the bloodstream from bone marrow cells is still not mature. Compared with other blood cells, mononuclear cells contain more nonspecific lipase, and has stronger phagocytosis. Stay in the blood mononuclear cells 2-3 days after transfer to the surrounding tissue, cell volume continues to increase, the diameter of up to 50-80 m, the number of cells containing lysosomal granules and mitochondria increased into mature cells. Mononuclear cells were fixed in tissues called tissue macrophages, they often exist in the lymph nodes, alveolar wall, bone marrow, liver and spleen. The activation of monocytes and tissue macrophages can generate and release a variety of cytotoxic, interferon and interleukin, participate in the body defense mechanism, but also produced some factors can promote the growth of endothelial cells and smooth muscle cells. Cell division in monocyte inflammation around, and surrounded by foreign body. The main purpose Monocytes can engulfing foreign antibodies, plays an important role in the invasion of pathogens in the body, resist cure injury and immunity to disease. The occurrence of inflammation or other diseases can be caused by the total number of mononuclear cells percentage change, so check the monocyte count has become an important method for the diagnosis of the. In the body, the immun