乳腺癌钼靶及病理诊断符合率及相关危险因素探析.docVIP

乳腺癌钼靶及病理诊断符合率及相关危险因素探析【摘 要】 目的:了解X线钼靶诊断乳腺癌与病理结果的符合率，探讨乳腺癌的发生与环境、社会等因素的关系。方法：广东省计生委资助立项“乳腺癌的钼靶与病理诊断符合率及相关因素多中心研究”课题，按照课题的设计和逆向追踪3～5年的临床积累，结合研究周期（2008年4月～2010年4月）内病例的收集，对2327例研究对象采用问卷进行调查。结果：（1）病例组和对照组的年龄、体重、身高、结婚年龄、民族、文化程度、婚姻状况等情况基本相同，差异不具有统计学意义；（2）钼靶诊断和病理诊断乳腺癌的符合率为94.9％；（3）乳腺癌发生的危险因素阳性研究结果有月经初潮年龄，性生活状况是否规律，是否隆胸，是否服用避孕药、激素，乳腺增生情况，是否患有乳腺囊肿、甲状腺疾病、高血压、肝病等，是否有肿瘤家族史，是否生育，是否容易发怒，酗酒或曾经历精神创伤等因素；（4）乳腺癌危险因素阴性研究结果有分娩流产次数，吸烟情况，睡眠情况，是否接收X线，乳腺外伤等因素。 结论：钼靶诊断能与病理诊断符合率高，这将有助于提高影像诊断乳腺癌的水平。乳腺癌的发生与环境、社会因素相关，如全面认识这些危险因素将有助于预防乳腺癌的发生。 【关键词】 乳腺癌; 钼靶诊断; 病理诊断; 符合率; 危险因素 Coincidence rate between molybdenum target check and pathological diagnosisof breast cancer and their related risk factors HE Wenshan1, WEN Qiaoping2, WU Zhaozhang1, JIA Qizhi1, MA Jie3, HE Shengxi1, XIE Zhaofeng4, WEI Wei5 1 Shenzhen Service Center of Family Planning, Guangdong 518028, China 2 Futian Street Service Station of Family Planning, Futian District, Guangdong 518028, China 3 Shenzhen People’s Hospital, Guangdong 518000, China 4 Shenzhen Maternal and Child Care Hospital, Guangdong 518000, China 5 Shenzhen Traditional Chinese Medicine Hospital, Guangdong 518000, China 【Abstract】 Objectives: To understand the coincidence rate of breast cancer by comparison of molybdenum target check and pathological findings, and to explore the occurrence of breast cancer and its relationship with environmental, social and other factors. Methods: A questionnaire survey was administered to 2327 cases with breast cancer in the last 4 years. Results: (1) Breast cancer group and the normal control groups were identical on the whole in age, weight, height, marriage age, ethnicity, education level, and marital status. (2) The coincidence rate between molybdenum target check diagnosis and pathological diagnosis of breast cancer was 94.9%. (3) Positive results of high risk factors for breast cancer were menarche age, sexual life status, breast implants, taking birth control pills and hormone drugs, breast hyperplasia