河源地区不孕症发病流行病学调查.docVIP

河源地区不孕症发病流行病学调查【摘 要】 目的:调查河源地区不育症发生情况及其影响因素。方法:整群抽样抽取源城区和东源县，应用统一问卷对2007年结婚育龄夫妇进行入户调查。资料统计采用一般性描述分析方法和卡方检验及多因素Logistic回归分析。结果:有效调查了2867对育龄夫妇，不孕症发病率为16.4%。夫妇女方年龄35岁以上组不孕症发生率（48.33%）远远高于其他年龄组，P=0.000；月经周期异常组的发生率（30.27%）与正常组比较有显著差异，P=0.000；月经量多或少组（22.63%）与中等量组比较差异有统计学意义。结论:河源地区不育症发生与女方年龄、月经状况等密切相关。 【关键词】 不孕症; 流行病学; 现况调查; 相关因素 The epidemiological investigation of infertility in heyuan region HUAN Qiaohai, XU Jia, HUANG Bilan, HUANG Jiangtao, WANG Qilng, HONG Yuzhen, ZHU Xiaoyong, YANG Xinqiong The family planning service center of dongyuan county of Guangdong province, Guangdong 517500, China 【Abstract】 Objectives: To investigate the incidence of infertility in Heyuan region of Guangdong province and explore the influencing factors. Methods:The couples married in 2007 from Yuancheng district and Heyuan county were selected by stratified cluster sampling in a cross-sectional study. Each of them was asked to answer a uniform questionnaire in the household survey. By means of general description, Chi-square test and multivariate Logistic regression analysis the data were analysed with SPSS13.0. Results: 2867 couples had been effectively investigated. The infertility rate was 16.4% in the whole area. The infertility rate of the group with female couple older than 35 years was higher than that of other groups(P=0.000). There was significant difference between the rate of the group for female couple with normal menstruation and that of the group with abnormal one(P=0.000). The infertility rate of the group for female couple with excessive or small menstrual was statistically different from that of group with moderate menstrual flow. Conclusions: The prevalenct of infertility was significantly affected by the factors such as female age, menstrual status in Heyuan region. 【Key words】 Infertility; Epidemiology; Cross-sectional; Influencing factors 不孕症是世界性的健康问题与社会医学问题。WHO预测21世纪不孕症将成为仅次于肿瘤和心脑血管疾患的第三大疾病，近年来该病的发病率呈上升趋势。WHO在31届年会报告中指出,各国的不孕率占育龄夫妇的5.10%～15%。我国的调查结