2 型糖尿病患者气虚证危险因素分析 - 国际中医中药杂志.pdf

·388 · 国际中医中药杂志2013年5月第35卷第5期 Int J Trad Chin Med, May 2013, Vol. 35, No.5 ·临床调研 · 2 型糖尿病患者气虚证危险因素分析 赵灵燕 毕力夫 马文杰 陈建新 赵慧辉 戴军有 王伟 【摘要】 目的 探讨 2 型糖尿病气虚证的主要危险因素，为研究防治糖尿病的中药提供依据。方 法 在流行病学调查基础上，得到 147 例符合 2 型糖尿病的病例，分为气虚证组、非气虚证组，运用单 因素、多因素非条件Logistic 回归方法分析气虚证的相关危险因素。结果 多因素非条件 Logistic 回归结 果表明，餐后 2 h 血糖[β值为－0.764，OR (95%CI)为 0.466 (0.236～0.919)]、载脂蛋白 B [β值为－1.005， OR (95%CI)为 0.366 (0.140～0.959)]、尿糖[β值为－1.300，OR (95%CI)为 0.273 (0.127～0.584)]，与 2 型 糖尿病患者的气虚证呈负相关。结论 2 型糖尿病气虚证与餐后 2 h 血糖、载脂蛋白B、尿糖呈负相关。 【关键词】 2 型糖尿病；证候；Logistic 回归分析 Analysis on risk factors of Qi deficiency syndrome of type 2 diabetes mellitusi ZHAO Ling-yan*, BI Li-fu, MA Wen-jie, CHEN Jian-xin, ZHAO Hui-hui, DAI Jun-you, WANG Wei. *Beijing University of Chinese Medicine, Beijing 100029, China Corresponding author：WANG Wei, Email：wangwei@bucm.edu.cn 【Abstract 】 Objective To explore the risk factors of Qi deficiency syndrome of type 2 diabetes mellitus and to provide evidence for prevention and cure diabetes mellitus with TCM. Methods On the basis of the epidemiological survey, 147 cases of Type 2 diabetes mellitus were collected and divided into Qi deficiency syndrome group and non-Qi deficiency syndrome group. The relationships between risk factors and Qi deficiency syndrome were analyzed by unconditional univariate and multivariate Logistic regression. Results β value is －0.764, OR (95%CI)is 0.466 (0.236 ～0.919)], Two hours postprandial blood sugar [2PPBS ( apolipoprotein-B [APo-B (β value is －1.005, OR (95%CI)is 0.366 (0.140～0.959)], urine glucose [β value is － 1.300, OR (95%CI)is 0.273 (0.127～0.584)] were inverse correlation with Qi deficiency syndrome of type 2 diabetes mellitus.