颈动脉低密度脂蛋白预测冠状动脉粥样硬化性心脏病探讨.docVIP

颈动脉、低密度脂蛋白预测冠状动脉粥样硬化性心脏病探讨 管一平△ 钱薇 邹翰琴 （宜宾市第二人民医院心内科，超声诊断科，四川 宜宾 644000） 【摘要】 目的 探讨应用颈动脉、低密度脂蛋白诊断作为预测冠状动脉粥样硬化性心脏病诊断指标的临床可行性。方法：对我院收治的经冠脉造影确诊的126例冠状动脉粥样硬化性心脏病（简称冠心病）患者，作双侧颈动脉彩色多普勒超声检查（简称彩超）及血浆脂质水平测定，用Cmuse法计算颈动脉斑块积分，研究颈动脉斑块积分与各低密度脂蛋白胆固醇(LDL-C）指标在预测冠状动脉粥样硬化性心脏病的可行性。结果：根据颈动脉彩色多普勒超声检查结果显示88.1%的冠心病患者颈动脉处增厚形成斑块，斑块的发生率达85.7%。以Crouse积分法判断将动脉是否有斑块发生为前提做LDL-C检查，有斑块的患者低密度脂蛋白指标高于没有斑块的患者，P＜0.05。结论：颈动脉彩超检测结合低密度脂蛋白检测对冠状动脉粥样硬化性心脏病的预测性诊断具有一定的指导性，但作为预测性诊断的标准仍需要大量的临床试验和科学的理论基础。 【关键词】 冠心病；颈动脉；彩色多普勒超声检查；低密度脂蛋白 Carotid artery, low density lipoprotein prediction coronary atherosclerotic heart disease is discussed. GUAN Yi-ping，QIAN Wei，ZOU Han-qin. Department of Cardiology, Ultrasound Department , The Second People’s Hospital of Yibin, Yibin Sichuan 644000,China 【Abstract】 Objective Discusses application carotid artery, low density lipoprotein diagnosis as prediction coronary atherosclerotic heart disease diagnosis index clinical feasibility. Methods In our hospital were diagnosed with angiographically of 126 cases of coronary atherosclerotic heart disease patients, double side carotid artery color doppler ultrasound and plasma lipid level determination, with Cmuse method for calculation of carotid plaques integral, the carotid plaques integral and the low-density lipoprotein (LDL) index in predicting coronary atherosclerotic heart disease is feasible. Results According to the carotid artery color doppler ultrasound examination results show that 85.7% of patients with coronary artery disease in carotid artery thickening, incidence of 88.1%. Crouse integral method to judge whether there is a plaque will artery occurred as the premise do LDL check, have plaques of patients with low density lipoprotein index is higher than no plaques of patients, P 0.05. Conclusion Carotid artery color dopplar ultrasound detection combined with low density lipoprotein detection for coronary artery disease diagnosis the predictability of the has certain directive, but as predictive diagnosis standard s