126例ICU侵袭性真菌感染临床研究.doc

126例ICU侵袭性真菌感染临床研究【摘要】目的 探讨ICU侵袭性真菌感染的易感因素和防止措施。方法 选取我院ICU2006年7月~2010年8月收治的126例侵袭性真菌感染患者的临床资料，观察并总结侵袭性真菌感染的易感因素、感染特点和治疗方法。结果 在本组126例患者中有114有基础疾病，占90.48%，其中以慢性肾病、慢性阻塞性肺疾病、白血病、系统性红斑狼疮最为多见。患者大都存在危险因素，如长期使用抗生素、糖皮质激素、糖尿病等。肺部真菌感染患者在临床无特异表现，确诊需要结合临床表现、痰培养和组织病理学。病原学以白色假丝酵母菌为主。应用抗真菌药物治疗，疗效安全、确切。结论 ICU侵袭性真菌感染的发病率呈逐年增加的趋势，老年人易感，菌种构成较前有改变，应适当调整抗真菌药物，积极采取综合治疗能够提高感染患者的治愈率。 【关键词】侵袭性真菌感染ICU 临床分析 中图分类号：R519文献标识码：A文章编号：1005-0515（2011）3-012-02 ICU of 126 cases of invasive fungal infections Li Ming （Baoshan City, Yunnan Province, People’s Hospital Critical Care Medicine, Baoshan 678000） 【Abstract】Objective To investigate the invasive fungal infection in ICU predisposing factors and prevention measures. Methods In our hospital ICU2006 July ~ August 2010 admitted 126 cases of invasive fungal infections in patients with clinical data, observations and summarizes the predisposing factors of invasive fungal infection, infection characteristics and treatment methods. Results In this group of 126 patients, 114 had underlying diseases, accounting for 90.48%, of which chronic kidney disease, chronic obstructive pulmonary disease, leukemia, systemic lupus erythematosus is most common. Most patients with risk factors exist, such as the long-term use of antibiotics, corticosteroids, diabetes. Pulmonary fungal infections in patients without specific clinical manifestations, diagnosis requires a combination of clinical presentation, sputum culture and histopathology. Pathogen Candida albicans to the main. Application of antifungal treatment, efficacy of safety, precise. Conclusion ICU the incidence of invasive fungal infection showed an increasing trend year by year, the elderly susceptible to changes in species composition than before, should be properly adjusted antifungal agents, and actively take comprehensive treatment can improve the cure rate of infection. 【Key words】Invasive fungal infection ICU Clinical Analysis 随着医疗技术的进步，ICU的兴起，危重病的救治水平越来越高，同时带来诸多问题，ICU患者的发病率逐渐增多，住