ICU发生院内感染危险因素Logistic回归研究.doc

ICU发生院内感染危险因素Logistic回归研究[摘要] 目的 调查研究ICU院内感染的发生情况和院内感染的相关危险因素，为预防ICU院内感染提供参考依据。方法 2009年2月～2011年5月在我院ICU住院的1092例患者，根据是否发生院内感染分为感染组和对照组，采用多因素非条件Logistic回归分析相关危险因素。结果 ICU患者发生院内感染率为26.28%，多因素结果显示，气管切开治疗、泌尿道插管治疗、住ICU时间＞10d、机械通气时间＞5d是ICU院内感染的独立危险因素。结论 ICU发生院内感染情况较为严重，气管切开治疗、泌尿道插管治疗、住ICU时间＞10d、机械通气时间＞5d是ICU院内感染的独立危险因素。 [关键词] 院内感染；重症监护病房；危险因素 [中图分类号] R181.3[文献标识码] B [文章编号] 1673-9701（2011）27-43-02 Logistic Regression Analysis for the Risk Factors of Nosocomial Infections in Intensive Care Unit WANG Bing Department of Intensive Care Unit，Zhoushan City Traditional Chinese Medicine and Orthopedics Union Hospital，Zhoushan 316000，China [Abstract] Objective To Investigate the occurrence of nosocomial infections and risk factors of patients in the ICU，and to supply a base of preservation for nosocomial infections in Intensive Care Unit. Methods The utilization of 1092 patients for in our hospital ICU from February 2009 to May 2011 were divided into infections group and control group according to whether the occurrence of nosocomial infections. Data was analyzed by multi-factor non-conditional Logistic regression analysis of risk factors. Results ICU patients with nosocomial infection rate was 26.28%，the results of multi-factor screening tracheotomy treatment，urinary tract catheterization，ICU stay time＞10d，mechanical ventilation＞5d were independent risk factors for nosocomial Infections in Intensive Care Unit. Conclusion ICU nosocomial infection is more severe，urinary tract catheterization，ICU stay time＞10d，mechanical ventilation＞5d were independent risk factors for nosocomial Infections in Intensive Care Unit. [Key words] Nosocomial infections；Intensive care unit；Risk factor 院内感染（nosocomial infections，NI）是指在医院获得的感染，包括在住院中和住院时、出院后2d内发生的感染，但不包括住院前已开始或处于潜伏期的感染[1]。近年来随着医学的发展及侵袭性操作的增多，医院感染问题越来越受到人们的关注和重视，而作为医院中高危患者集中的重症监护病房（intensive care unit，ICU）因为有较多的介入性诊疗措施，并且患者病情危重从而导致ICU院内感染比普通病房高3～18倍左右[2]，因此研究ICU患者医院感染的现状及其危险因素，对其院内感染预防有着积极的意义，为此本研究对2009年2月～2011年5月在我院ICU住