六味安消胶囊对功能性消化不良患者胃排空影响.docVIP

六味安消胶囊对功能性消化不良患者胃排空影响[摘要] 目的 观察六味安消胶囊对功能性消化不良患者的临床疗效及对胃排空、胃动素的影响。方法 72例功能性消化不良患者随机分为两组:治疗组和对照组。全部停止应用影响胃酸分泌及胃动力的药物一周后,给予症状评分,并进行胃排空、空腹血浆胃动素的检测;对照组给予多潘立酮口服2周,治疗组给予六味安消胶囊(邦消安)口服2周,然后再次进行症状评分并检测胃排空、空腹血浆胃动素的变化。结果 (1)FD患者口服六味安消胶囊2周后,上腹痛、腹胀、早饱、嗳气等临床症状明显改善,症状积分与治疗前比较有统计学意义(P0.05)。(2)FD患者治疗后与治疗前胃排空率比较:2h、5h胃全排空例数及胃排空率均明显增加(P0.05)。(4)FD患者治疗后与治疗前空腹血浆胃动素相比明显增加(P0.05)。结论 六味安消胶囊可显著改善功能性消化不良患者的上腹痛、腹胀、早饱、嗳气等主要症状,改善胃动力,加速胃排空,提高空腹血浆胃动素。 [关键词] 功能性消化不良;六味安消胶囊;胃排空 [中图分类号] R57[中图分类号] A[文章编号] 1673-9701(2009)24-95-03 Effect of Liuweianxiao Capsules on the Gastric Emptyiny of Functional Dyspepsia Patients DU Wenzhen1WEI Liangzhou2 Wanhua Hospital of Yantai City,Shandong Yantai 264000,China; 2.The Affiliated Hospital of Medical College Qingdao University,Shandong 266000,China [Abstract] Objective To observe clinical efficacy of gastric emptying,motilin of the Liuweianxiao Capsules on the patients with functional dyspepsia. Methods Seventy-two cases of patients with functional dyspepsia were randomly divided into two groups:the treatment group and control group. All to stop the application of the impact of gastric acid secretion and gastric motility after a week of drug given symptom score and gastric emptying,fasting plasma motilin Detection; the control group were given oral domperidone 2 weeks,treatment groups were given Liuwei anxiao capsule oral 2 weeks,and then again Detect symptom score and gastric emptying,fasting plasma motilin changes. Results (1)FD patients with an oral capsule Liuwei anxiao 2 weeks later,on abdominal pain,bloating,early satiety,belching and other clinical symptoms markedly improved,and the symptom score before treatment were statistically significant(P0.05). (2)FD patients with gastric emptying rate of pre-treatment:2 hours, 5 hours the whole gastric emptying and gastric emptying rate of the number of cases were significantly increased(P0.05). (4)FD patients with pre-treatment fasting plasma motilin increased significantly(P0.05). Conclusion Liu